Patents Assigned to GenVex, Inc.
  • HIV vaccines based on adenoviral vectors encoding Env from multiple clades of HIV
    Patent number: 8323961
    Abstract: The invention provides a composition comprising four adenoviral vectors, each comprising a nucleic acid sequence encoding a clade A HIV Env protein, a clade B HIV Env protein, a clade C HIV Env protein, and a clade B HIV Gag-Pol fusion protein, respectively. The invention also provides a method of inducing an immune response against HIV-1 in an animal comprising administering the composition to the animal.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: December 4, 2012
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, GenVex, Inc.
    Inventors: Gary J. Nabel, Bimal Chakrabarti, Wing-Pui Kong, Yue Huang, Zengguang Wang, legal representative, Zhi-Yong Yang, Jason G. D. Gall, C. Richter King