Patents Assigned to GENZYME CORP.
  • Methods for treating cancer
    Patent number: 10953003
    Abstract: The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: March 23, 2021
    Assignees: X4 PHARMACEUTICALS, INC., GENZYME CORP.
    Inventors: Paula Marie Ragan, Robert D. Arbeit, Kieran James Crowley
  • METHODS FOR TREATING CANCER
    Publication number: 20180369229
    Abstract: The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.
    Type: Application
    Filed: December 14, 2016
    Publication date: December 27, 2018
    Applicants: X4 Pharmaceuticals, Inc., Genzyme Corp.
    Inventors: Paula Marie Ragan, Robert D. Arbeit, Kieran James Crowley
  • Use of CXCR4 Antagonists
    Publication number: 20150030561
    Abstract: Presently disclosed are methods and compositions for treating or preventing WHIM syndrome and certain other disorders or conditions with a certain CXCR4 antagonist.
    Type: Application
    Filed: May 15, 2012
    Publication date: January 29, 2015
    Applicants: GENZYME CORP., UNIVERSITY OF WASHINGTON CENTER FOR COMMERCIALIZATION
    Inventors: David C. Dale, Gary J. Bridger, Frank J. Hsu