Patents Assigned to GEORGE-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENLICHEN RECHTS, UNIVERSITAETSMEDIZIN
  • Methods of producing bioengineered neuronal organoids (BENOs) and uses thereof
    Patent number: 11781109
    Abstract: The present invention relates to the field of in vitro 3D modeling of neural tissues, particularly of the brain. There is the need of developing cell culture models of neural tissue that reflect physiological aspects of neural tissue. The present invention provides methods of producing bioengineered neuronal organoids (BENOs) which form functional neuronal networks. The present invention also relates to uses and applications of the produced BENOs, e.g., in the fields of drug screening and personalized medicine.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: October 10, 2023
    Assignee: GEORGE-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENLICHEN RECHTS, UNIVERSITAETSMEDIZIN
    Inventors: Wolfram-Hubertus Zimmermann, Maria Zafeiriou