Abstract: The present invention provides methods for treating Cryptococcus neoformans and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a dicationic bis-benzimidazole in an amount effective to treat the conditions.
Type:
Grant
Filed:
May 1, 1996
Date of Patent:
June 17, 1997
Assignees:
University of North Carolina, Duke University, Georgia State Univ. Research Foundation
Inventors:
Christine C. Dykstra, John Perfect, David W. Boykin, W. David Wilson, Richard R. Tidwell