Abstract: The present invention demonstrates for the first time that alpha-methyl-tryptophan is an inhibitor of the enzyme indoleamine diooxygenase (IDO). The present invention includes the use of alpha-methyl-tryptophan in methods of modulating immune responses and treating cancer and infections.
Type:
Application
Filed:
February 9, 2011
Publication date:
June 6, 2013
Applicant:
Georiga Health Sciences Univ. Research Inst., Inc.