Patents Assigned to GERMAN CANCER RESEARCH CENTER (DKFZ)
  • Mutations of histone proteins associated with proliferative disorders
    Patent number: 9494591
    Abstract: The present application shows the relationship between variations in the amino acid sequence of histone proteins, more specifically the H3.3 protein, and proliferation-associated disorders. Herewith provided are predictive methods, commercial packages, therapeutic methods and screening methods based on this relationship.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: November 15, 2016
    Assignees: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, UNIVERSITÄTSKLINIKUM HEIDELBERG, GERMAN CANCER RESEARCH CENTER (DKFZ)
    Inventors: Nada Jabado, Stefan M. Pfister, Christoph Plass, Andrey Korshunov, Hendrik Witt, Dominik Sturm, David Jones, Peter Lichter, Elke Pfaff