Abstract: Method for producing a cell sensor system for the definition of quality criteria during the production of materials, characterised by the following method steps: a) cultivation of first cells of a specific type under standardised culture conditions (control group), b) cultivation of second cells of the specific type on/in/between different materials to be tested (test group), c) harvesting of the cells, d) determination of the gene activities of the cells of the control group and of the cells of the test group, e) comparison of the gene activities of the test group with the control group, f) identification of the genes for which there is a difference in the gene activities between the control group and the test group, g) construction of a microarray using the identified genes with different gene activity as the gene profile, this created microarray being defined as the standard for the specific cell type, and h) provision of third cells of the specific cell type as cell sensor.