Patents Assigned to GH Care, Inc.
  • Alginate microcapsules for cell and molecular therapy that secrete bioactive immune molecules
    Patent number: 11096898
    Abstract: A membrane including a barrier having layers of alginate with different material molar concentrations relative to another material. The layers have a uniform consistency across a thickness of the layers. The thickness is free of laminae and interfaces and forms a single layer morphology that provides permeability for selected molecules.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: August 24, 2021
    Assignee: GH CARE INC.
    Inventors: Giuseppe Pietro Pio Basta, Pia Montanucci, Riccardo Calafiore
  • Microencapsulation process of sertoli cells, microcapsules obtained and use for treatment of type I diabetes mellitus
    Patent number: 8865218
    Abstract: The invention relates to the use of Sertoli cells (SC) microencapsulated into hydrogel-based microcapsules, for the prevention and/or treatment of Type 1 diabetes mellitus (T1DM) and to a process for producing microcapsules, preferably shaped as microspheres.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: October 21, 2014
    Assignee: GH Care, Inc.
    Inventors: Riccardo Calafiore, Giovanni Luca, Mario Calvitti, Ennio Becchetti, Paolo Puccetti, Francesca Fallarino, Claudio Nastruzzi
  • PROCESS FOR THE ULTRAPURIFICATION OF ALGINATES
    Publication number: 20140275519
    Abstract: A method for obtaining solutions of non-structurally modified salts of alginate, with endotoxin content less than 20 EU/g includes obtaining an alginate solution having a concentration ranging from 1.6 to 2.0% by weight by adding commercial grade alginate powder to a saline solution. The alginate solution obtained is filtered on at least one hydrophilic filter, and a filtered alginate solution is recovered. The filtered alginate solution obtained is further filtered on a charge-modified hydrophobic filter, and an alginate solution having an endotoxin content less than 20 EU/g is recovered.
    Type: Application
    Filed: May 30, 2014
    Publication date: September 18, 2014
    Applicant: GH Care, Inc. d/b/a Altucell, Inc.
    Inventors: Giuseppe Pietro Pio Basta, Riccardo Calafiore
  • Process for the ultrapurification of alginates
    Patent number: 8765937
    Abstract: A process for the ultrapurification of alginates is provided. In particular, the process may be used for microencapsulation in human cell transplants.
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: July 1, 2014
    Assignee: GH Care, Inc.
    Inventors: Giuseppe Pietro Pio Basta, Riccardo Calafiore