Abstract: A method for obtaining solutions of non-structurally modified salts of alginate, with endotoxin content less than 20 EU/g includes obtaining an alginate solution having a concentration ranging from 1.6 to 2.0% by weight by adding commercial grade alginate powder to a saline solution. The alginate solution obtained is filtered on at least one hydrophilic filter, and a filtered alginate solution is recovered. The filtered alginate solution obtained is further filtered on a charge-modified hydrophobic filter, and an alginate solution having an endotoxin content less than 20 EU/g is recovered.
Type:
Application
Filed:
May 30, 2014
Publication date:
September 18, 2014
Applicant:
GH Care, Inc. d/b/a Altucell, Inc.
Inventors:
Giuseppe Pietro Pio Basta, Riccardo Calafiore