Patents Assigned to Giam Pharma International SARL.
  • Calixpyrrole-based antitumor compounds
    Patent number: 10799480
    Abstract: Calixpyrrole-based antitumor compounds such as compounds of Formula IX: are described, which can be derivatized to obtain their passive transport on tumor masses through the Enhanced Permeation and Retention, EPR, effect of the neoplastic vasculature. The conjugation of the above-mentioned compounds with peptides/antibodies is further described, for their possible active transport on tumor cells.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: October 13, 2020
    Assignee: Giam Pharma International SARL.
    Inventors: Franz Heinrich Kohnke, Alberto Izzotti, Camillo Rosano, Grazia Cafeo