Patents Assigned to Gibipharma S.p.A.
  • Pyrrolidin-2-one derivatives having nootropic activity
    Patent number: 4788212
    Abstract: Pyrrolidin-2-one derivatives of formula I: ##STR1## wherein X=H, OH, C.sub.2 -C.sub.7 acyloxy, C.sub.1 -C.sub.6 alkoxy, cycloalkoxy or phenoxy, n=0 or 1 and m=2 or 3, have a marked nootropic activity.
    Type: Grant
    Filed: July 29, 1987
    Date of Patent: November 29, 1988
    Assignees: Gibipharma S.p.A., Istituto Biochimico Italiano Giovanni Lorenzini S.p.A.
    Inventor: Silvia Scolastico
  • Stable salts of S-adenosyl-L-methionine with polyanions
    Patent number: 4764603
    Abstract: Stable salts of S-adenosyl-L-methionine with water-soluble polyanions, such as polyphosphates, polyvinylsulfonates -sulfates or -phosphates, polyacrylates, polystyrene sulfonates, are described.The salts according to the invention, prepared by precipitation from aqueous solutions of pH not exceeding 3.5, possess peculiar stability, solubility, nonhygroscopicity and are valuable for use as active constituents in pharmaceutical compositions.
    Type: Grant
    Filed: August 9, 1985
    Date of Patent: August 16, 1988
    Assignee: Gibipharma S.p.A.
    Inventors: Vincenzo Zappia, Mario De Rosa