Patents Assigned to Gilead Apollo, LLC
  • Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof
    Patent number: 11912718
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Grant
    Filed: August 3, 2021
    Date of Patent: February 27, 2024
    Assignee: Gilead Apollo, LLC
    Inventor: Xiaowei Yang
  • Solid forms for a thienopyrimidinedione ACC inhibitor and methods for production thereof
    Patent number: 11104687
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: August 31, 2021
    Assignee: Gilead Apollo, LLC
    Inventors: Geraldine C. Harriman, Jon P. Lawson, Xiaowei Yang
  • Ester ACC inhibitors and uses thereof
    Patent number: 11098055
    Abstract: The present invention provides ester compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: August 24, 2021
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • Pyrazole ACC inhibitors and uses thereof
    Patent number: 10941158
    Abstract: The present invention provides pyrazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: March 9, 2021
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei
  • Pesticidal compositions and uses thereof
    Patent number: 10941157
    Abstract: Provided herein are compounds that exhibit activity as fungicides and are useful, for example, in methods for the control of fungal pathogens in plants and can be applied to said plants in a variety of ways.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: March 9, 2021
    Assignee: Gilead Apollo, LLC
    Inventors: Jennifer Lynn Bennett, Karen C. Fitzsimmons, Shomir Ghosh, Jeremy Robert Greenwood, William P. Haakenson, Jr., Geraldine C. Harriman, Silvana Marcel Leit De Moradei, Barry J. Shortt, Urszula J. Slomczynska, Jeffrey Michael Stein
  • Triazole ACC inhibitors and uses thereof
    Patent number: 10800791
    Abstract: The present invention provides triazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: October 13, 2020
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof
    Patent number: 10487090
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: November 26, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Jon P. Lawson, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Xiaotian Wang, Xiaowei Yang
  • ACC inhibitors and uses thereof
    Patent number: 10472374
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: November 12, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Sathesh Bhat, Jeremy Robert Greenwood, Geraldine C. Harriman, James Harwood, Craig E. Masse
  • ACC inhibitors and uses thereof
    Patent number: 10208044
    Abstract: The present invention provides for compounds of formula I as acetyl-CoA carboxylase (ACC) inhibitors. The ACC inhibitors are useful for the prevention or treatment of metabolic syndrome, including obesity, dyslipidemia and hyperlipidemia in humans. The inhibitor compounds are also capable of inhibiting the ACC enzyme found in plants, parasites and bacteria.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 19, 2019
    Assignee: GILEAD APOLLO, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • ACC inhibitors and uses thereof
    Patent number: 10208063
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same. Specifically, bicyclic heteroaryl derivatives containing a imidazole, thiazole or oxazole fused to a pyridinone, pyrimidinone or pyrimidindione are provided. These compounds have therapeutic utility toward treating an ACC enzyme mediated disorder such as obesity in a subject, upon administration in an effective amount to said subject.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 19, 2019
    Assignee: GILEAD APOLLO, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof
    Patent number: 10183951
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: January 22, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: John C. Amedio, Jr., Sijun Hu, Henry Morrison
  • ACC inhibitors and uses thereof
    Patent number: 10179793
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: January 15, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Jeremy Robert Greenwood
  • Bicyclic compounds as ACC inhibitors and uses thereof
    Patent number: 9988399
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: June 5, 2018
    Assignee: Gilead Apollo, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • ACC inhibitors and uses thereof
    Patent number: 9944655
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: April 17, 2018
    Assignee: Gilead Apollo, LLC
    Inventors: Geraldine C. Harriman, Craig E. Masse, H. James Harwood, Sathesh Bhat, Jeremy Robert Greenwood
  • ACC inhibitors and uses thereof
    Patent number: 9765089
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: September 19, 2017
    Assignee: Gilead Apollo, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • ACC INHIBITORS AND USES THEREOF
    Publication number: 20170145028
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: October 26, 2016
    Publication date: May 25, 2017
    Applicant: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Geraldine C. Harriman