Patents Assigned to Gilupi GmbH
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Patent number: 10383605Abstract: Device for the in-vivo and/or in-vitro enrichment of target structures in a sample liquid, including at least one functional portion, which is provided with receptors for enriching the target structures. In order to improve the enrichment of the target structures in the sample liquid, it is provided according to the invention that the functional portion has a helical shape, which is produced by twisting a symmetrical starting cross section about a twisting axis. The invention likewise discloses a method for producing this device.Type: GrantFiled: January 20, 2016Date of Patent: August 20, 2019Assignee: GILUPI GMBHInventors: Robert Niestroj-Pahl, Klaus Lücke, Solveigh Krusekopf, Frank Daniel Scherag, Jürgen Rühe, Thomas Brandstetter
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Patent number: 10352931Abstract: The present invention provides a diagnostic device allowing highly specific and efficient in vivo and/or in vitro detection of a bio marker in a broad range of bodily fluids or tissues. The diagnostic device is composed of a binding agent that specifically binds a bio marker present in the bodily fluid linked by a linker compound or layer to the substrate, which includes a metallic, a semiconductor, or a polymeric carrier. The present invention further provides methods using said device for the detection of bio markers, as well as kits comprising said device and suitable ingredients for the detections of bio markers in a bodily fluid. Furthermore, the invention provides suitable in vivo and in vitro applications of said binding agent for the detection of specific disease-related target structures.Type: GrantFiled: August 27, 2014Date of Patent: July 16, 2019Assignee: GILUPI GMBHInventor: Björn Nowack
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Patent number: 10314524Abstract: The invention relates to a device for detecting analytes. In order to supply a need in alternative prenatal diagnostic methods which do not include the risks known in the state of art, the present invention provides a device for detecting analytes, including a polymer fiber and capturing molecules, wherein the capturing molecules bind to an analyte and/or a linker molecule.Type: GrantFiled: September 23, 2009Date of Patent: June 11, 2019Assignee: GILUPI GMBHInventors: Klaus Lücke, Ekkehardt Weber, Robert Müller, Andreas Bollmann, Oliver Harnack
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Patent number: 10178966Abstract: The invention relates to a detection device for the in vivo and/or in vitro enrichment of sample material, comprising a functional surface charged with detection receptors. To ensure the diagnosis of different diseases using a detection device of the type mentioned at the outset with less efforts and an improved precision of the diagnosis, it is provided according to the invention that the detection device comprises at least one guide element and at least two functional elements disposed at the guide element, wherein a functional surface charged with detection receptors is formed at each of them, the functional elements being designed for being detachable from each other and/or individually detachable from the guide element. Furthermore, the invention provides a use of and a method for the application of said detection device.Type: GrantFiled: May 29, 2014Date of Patent: January 15, 2019Assignee: GILUPI GMBHInventors: Klaus Lucke, Robert Niestroj, Andreas Bollmann
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Patent number: 10022109Abstract: The present invention refers to a detection device for the in vivo and/or in vitro enrichment of sample material, the detection device comprising a functional surface equipped with detection receptors. To further improve the enrichment of sample material by using a detection device of the aforementioned type, it is provided according to the invention that the functional surface has a three-dimensional structure with mutually facing functional sections which form spaces that can be filled with a sample liquid. Furthermore, the present invention provides for a use and for a method for the use of the detection device.Type: GrantFiled: June 17, 2010Date of Patent: July 17, 2018Assignee: GILUPI GMBHInventors: Klaus Lücke, Andreas Bollmann, Steffi Mewes, Robert Niestroj
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Publication number: 20140357967Abstract: The invention relates to a detection device for the in vivo and/or in vitro enrichment of sample material, comprising a functional surface charged with detection receptors. To ensure the diagnosis of different diseases using a detection device of the type mentioned at the outset with less efforts and an improved precision of the diagnosis, it is provided according to the invention that the detection device comprises at least one guide element and at least two functional elements disposed at the guide element, wherein a functional surface charged with detection receptors is formed at each of them, the functional elements being designed for being detachable from each other and/or individually detachable from the guide element. Furthermore, the invention provides a use of and a method for the application of said detection device.Type: ApplicationFiled: May 29, 2014Publication date: December 4, 2014Applicant: GILUPI GmbHInventors: Klaus Lucke, Robert Niestroj, Andreas Bollmann
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Patent number: 8846580Abstract: This invention relates generally to biosensor technology, and pertains more particularly to novel multifunctional biosensors based on ordered arrays of metallic, semiconductors and magnetic nano-islands for medical, biological, biochemical, chemical and environmental applications.Type: GrantFiled: June 9, 2006Date of Patent: September 30, 2014Assignee: Gilupi GmbHInventors: Ulrich Pison, Michael Giersig, Alex Schaefer
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Publication number: 20130197334Abstract: The invention concerns a Biodetector with a functionalised surface for isolating molecules or cells from the human body. In order to improve a Biodetector of the type mentioned above such that the functionalised surface of the Biodetector or there upon enriched molecules or cells are exposed to a lower abrasion, and the biocompatibility of the Biodetector is improved, the Biodetector is designed to remove a fluid from the human body and absorb it into an inner space of the Biodetector, wherein the functionalised surface is oriented to the inner space of the Biodetector.Type: ApplicationFiled: March 15, 2011Publication date: August 1, 2013Applicant: GILUPI GMBHInventors: Ekkehardt Weber, Robert Niestroj
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Publication number: 20120237944Abstract: The present invention refers to a detection device for the in vivo and/or in vitro enrichment of sample material, the detection device comprising a functional surface equipped with detection receptors. To further improve the enrichment of sample material by using a detection device of the aforementioned type, it is provided according to the invention that the functional surface has a three-dimensional structure with mutually facing functional sections which form spaces that can be filled with a sample liquid. Furthermore, the present invention provides for a use and for a method for the use of the detection device.Type: ApplicationFiled: June 17, 2010Publication date: September 20, 2012Applicant: GILUPI GMBHInventors: Klaus Lücke, Andreas Bollmann, Steffi Mewes, Robert Niestroj
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Patent number: 8197756Abstract: This invention relates generally to biosensor technology, and pertains more particularly to novel multifunctional biosensors based on ordered arrays of metallic, semiconductors and magnetic nano-islands for medical, biological, biochemical, chemical and environmental applications.Type: GrantFiled: April 11, 2007Date of Patent: June 12, 2012Assignee: Gilupi GmbHInventors: Ulrich Pison, Michael Giersig, Alex Schaefer
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Publication number: 20110301442Abstract: The invention relates to a device for detecting analytes. In order to supply a need in alternative prenatal diagnostic methods which do not include the risks known in the state of art, the present invention provides a device for detecting analytes, including a polymer fiber and capturing molecules, wherein the capturing molecules bind to an analyte and/or a linker molecule.Type: ApplicationFiled: September 23, 2009Publication date: December 8, 2011Applicant: Gilupi GmbHInventors: Klaus Lücke, Ekkehardt Weber, Robert Müller, Andreas Bollmann, Oliver Harnack
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Publication number: 20090131274Abstract: This invention relates generally to biosensor technology, and pertains more particularly to novel multifunctional biosensors based on ordered arrays of metallic, semiconductors and magnetic nano-islands for medical, biological, biochemical, chemical and environmental applications.Type: ApplicationFiled: June 6, 2006Publication date: May 21, 2009Applicant: GILUPI GMBHInventors: Ulrich Pison, Michael Giersig, Alex Schaefer
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Publication number: 20080213130Abstract: This invention relates generally to biosensor technology, and pertains more particularly to novel multifunctional biosensors based on ordered arrays of metallic, semiconductors and magnetic nano-islands for medical, biological, biochemical, chemical and environmental applications.Type: ApplicationFiled: April 11, 2007Publication date: September 4, 2008Applicant: GILUPI GmbHInventors: Ulrich Pison, Michael Giersig, Alex Schaefer