Abstract: Conjugates of a carrier molecule and an organic molecule producing singlet oxygen after irradiation are useful in diagnostic and therapeutic applications. The organic molecule is a terthienyl or terfuranyl compound derivatized to react with amino, thiol, or saccharide groups of the carrier molecule. Suitable carrier molecules include antibodies, peptides, haptamers, sugars, and other analogous molecules which direct the organic molecule to a biological target.
Type:
Grant
Filed:
November 22, 1996
Date of Patent:
February 9, 1999
Assignees:
Giovanni Neri, L. Molenti & C. Dei Fratelli Alitti Societa' Di Esercizio Societa' Per Azioni