Patents Assigned to Gist Brocades Italy Spa
  • Process for the synthesis of amikacin
    Patent number: 5763587
    Abstract: In the synthesis of amikacin, having the formula: ##STR1## by acylation of a diprotected derivative of kanamycin A with a reactive derivative of L-(-)-4-amino-2-hydroxybutyric acid, the selection of the reaction solvent and of the pH conditions permit the industrial economically and the synthesis yield to be improved.
    Type: Grant
    Filed: February 14, 1992
    Date of Patent: June 9, 1998
    Assignee: Gist Brocades Italy Spa
    Inventor: Alberto Mangia