Abstract: The present invention relates to the use of a specific inhibitor of Smad7 expression or function for the preparation of a pharmaceutical composition for the prevention, amelioration or treatment of a disease of the central nervous system and/or diseases related and/or caused by said disease of the central nervous system. Furthermore, methods for preventing, ameliorating and/or treating such diseases are disclosed.
Type:
Grant
Filed:
October 31, 2002
Date of Patent:
April 20, 2010
Assignee:
Giuliani International, Ltd.
Inventors:
Andreas Steinbrecher, Gerhard Giegerich, Ingo Kleiter, Markus Horn, Rainer Apfel, Roland Kreutzer, Stefan Limmer, Hans-Peter Vornlocher