Patents Assigned to Giuliani S.p.A
  • Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
    Patent number: 5057509
    Abstract: Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by reacting with succinic acid carbonanions the corresponding derivatives which have previously been protected, and subsequently deprotecting and decarboxylating them.
    Type: Grant
    Filed: April 9, 1990
    Date of Patent: October 15, 1991
    Assignee: Giuliani S.p.A.
    Inventors: Roberto Pellicciari, Aldo Roda, Giuliano Frigerio