Patents Assigned to GLADIATOR BIOSCIENCES, INC.
  • Method of targeting exosomes
    Patent number: 11981723
    Abstract: A method of targeting extracellular vesicles employing a molecule comprising a GLA domain and extracellular vesicles obtained or obtainable from a method are described herein.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: May 14, 2024
    Assignee: GLADIATOR BIOSCIENCES, INC.
    Inventors: Terry Hermiston, Maxine Bauzon, Christopher H. Contag, Jonathan Hardy, Masamitsu Kanada
  • GLA DOMAINS AS TARGETING AGENTS
    Publication number: 20210113657
    Abstract: The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis. These proteins can be linked to both diagnostic and therapeutic payloads, thereby permitting identification and treatment of cells expression elevated PtdS.
    Type: Application
    Filed: December 18, 2020
    Publication date: April 22, 2021
    Applicant: GLADIATOR BIOSCIENCES, INC.
    Inventors: Maxine BAUZON, Terry HERMISTON
  • METHOD OF TARGETING EXOSOMES
    Publication number: 20210062143
    Abstract: The present disclosure relates to a method of targeting extracellular vesicles employing a molecule comprising a GLA domain and extracellular vesicles obtained or obtainable from a method disclosed herein.
    Type: Application
    Filed: September 5, 2018
    Publication date: March 4, 2021
    Applicant: GLADIATOR BIOSCIENCES, INC.
    Inventors: Terry HERMISTON, Maxine BAUZON, Christopher H. CONTAG, Jonathan HARDY, Masamitsu KANADA
  • GLA domains as therapeutic agents
    Patent number: 10925926
    Abstract: The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: February 23, 2021
    Assignee: GLADIATOR BIOSCIENCES, INC.
    Inventors: Maxine Bauzon, Terry Hermiston
  • GLA DOMAINS AS THERAPEUTIC AGENTS
    Publication number: 20210015900
    Abstract: The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis.
    Type: Application
    Filed: September 25, 2020
    Publication date: January 21, 2021
    Applicant: GLADIATOR BIOSCIENCES, INC.
    Inventors: Maxine BAUZON, Terry HERMISTON
  • Gla domains as targeting agents
    Patent number: 10894075
    Abstract: The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis. These proteins can be linked to both diagnostic and therapeutic payloads, thereby permitting identification and treatment of cells expression elevated PtdS.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 19, 2021
    Assignee: GLADIATOR BIOSCIENCES, INC.
    Inventors: Maxine Bauzon, Terry Hermiston
  • DELIVERY OF PAYLOADS TO STEM CELLS
    Publication number: 20200407421
    Abstract: The present disclosure relates to a method of targeting stems cells, in particular non-apoptotic stem cells, employing a GLA domain, capable of binding surface exposed phosphatidyl serine.
    Type: Application
    Filed: September 5, 2018
    Publication date: December 31, 2020
    Applicant: GLADIATOR BIOSCIENCES, INC.
    Inventors: Terry HERMISTON, Maxine BAUZON, Christopher H. CONTAG, Jonathan HARDY, Francis Gerard BLANKENBERG
  • A METHOD OF INTRACELLULAR DELIVERY
    Publication number: 20200407422
    Abstract: The present disclosure relates to a method of intracellular delivery of a molecule employing a GLA domain to facilitate entry into the cell.
    Type: Application
    Filed: September 5, 2018
    Publication date: December 31, 2020
    Applicant: GLADIATOR BIOSCIENCES, INC.
    Inventors: Terry HERMISTON, Maxine BAUZON, Christopher H. CONTAG, Jonathan HARDY, Francis Gerard BLANKENBERG
  • GLA DOMAINS AS THERAPEUTIC AGENTS
    Publication number: 20190105370
    Abstract: The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis.
    Type: Application
    Filed: October 25, 2018
    Publication date: April 11, 2019
    Applicant: GLADIATOR BIOSCIENCES, INC.
    Inventors: Maxine BAUZON, Terry HERMISTON