Abstract: A composition for releasing nitric oxide which provides a rapid release of nitrogen monoxide, and also allows formation of S-nitrosothiol compounds which provide a slower extended release of nitrogen monoxide. A composition kit includes two components that are mixed together to initiate nitric oxide release. The kit includes: a liquid phase comprising a solvent and at least one reducing agent; and a solid phase comprising a nitrate and/or nitrite salt, copper ions and at least one thiol. A method of treating sexual dysfunction involves topically applying the composition to an area of the subject to be treated.
Type:
Grant
Filed:
March 19, 2018
Date of Patent:
July 21, 2020
Assignee:
Glanotech Limited
Inventors:
Gioacchino Di Leo, Luciano Caglioti, Alberto Boffi, Luciana Mosca, Robert Giovanni Nisticò