Abstract: The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and diabetes.
Type:
Application
Filed:
June 2, 2010
Publication date:
March 29, 2012
Applicant:
GLAXSMITHKLINE LLC
Inventors:
Siegfried Benjamin Christensen IV, Donghui Qin, Shi Lu, Shuai Wei, Nianyong Yang, Zhiliu Zhang
Abstract: The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and diabetes.
Type:
Application
Filed:
June 2, 2010
Publication date:
March 29, 2012
Applicant:
GLAXSMITHKLINE LLC
Inventors:
Siegfried Benjamin Christensen, IV, Donghui Qin, Shenglin Chen, Xing Huang, Di Li, Fei Li, Xiaojuan Lin, Shi Lu, Maoyun Lv, Chengde Wu, Weiliang Xu, Gang Yan, Jianxing Yuan, Weina Zhang, Zhiliu Zhang