Abstract: A solid crystalline form of 1-(2-[4-(6-methoxy-3,4-dihydronaphthalene-1-y) phenoxy]ethyl)pyrrolidine, and a preparing process thereof are provided. The aforesaid compound is a key intermediate in the synthesis of lasofoxifene. A process for preparing lasofoxifene, a process for purifying lasofoxifene tartrate, and a crystalline form of lasofoxifene tartrate are also provided.
Type:
Application
Filed:
April 27, 2010
Publication date:
February 23, 2012
Applicant:
GLENMARK GENERRICS LTD
Inventors:
Mubeen Ahmed Khan, Nikhil Rasiklal Trivedi, Nagan Nirmalan Kandasamy, Dayaghan Gangadhar Patil, Vipin Kumar Pandey