Patents Assigned to Global Life Sciences Solutions Operations UK Ltd
  • Patent number: 10907201
    Abstract: The present invention relates to compositions, methods and kits which can be used to amplify nucleic acids with the advantage of decreasing user time and possible contamination. The dried reagent composition of the invention can be used for easy processing and amplification of nucleic acid samples.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: February 2, 2021
    Assignee: Global Life Sciences Solutions Operations UK Ltd
    Inventors: Jeffrey K. Horton, Peter J. Tatnell, Kathryn L. Lamerton
  • Patent number: 10907148
    Abstract: The present invention relates to a method and kit for analyte detection. More precisely the invention relates to a method of detecting an analyte, comprising storing short single stranded nucleic acids (10-100 nt), such as aptamers and micro RNA, on a solid support at ambient temperature; and subsequent amplification of said nucleic acids for detection of analyte(s).
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: February 2, 2021
    Assignee: Global Life Sciences Solutions Operations UK Ltd
    Inventors: Jeffrey Kenneth Horton, Peter James Tatnell
  • Patent number: 10876938
    Abstract: The present invention relates to solid supports that are used for the storage and further processing of biological materials. The invention is particularly concerned with solid supports which have at least one surface coated with a chemical that enhances the recovery of the biological material from the support. Methods of preparing and using the solid supports are also described.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: December 29, 2020
    Assignee: Global Life Sciences Solutions Operations UK Ltd
    Inventors: Jeffrey Kenneth Horton, Peter James Tatnell, Simon Laurence John Stubbs
  • Patent number: 10870845
    Abstract: A method is provided herein, wherein the method of capturing a target nucleic acid, comprises applying a nucleic acid capture probe to a capture zone of a needs definition, wherein the nucleic acid capture probe having a first molecular weight comprises at least a sequence that is complimentary to at least a portion of the target nucleic acid sequence and the nucleic acid capture probe is substantially immobilized at the capture zone of the substrate. The method further comprises applying a sample comprising the target nucleic acid having a second molecular weight to a sample application zone of the substrate; wherein the sample comprising the target nucleic acid flows across a length of the substrate from the sample application zone to the capture zone by lateral flow, and the target nucleic acid is captured by the nucleic acid capture probes by hybridization to the capture zone.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: December 22, 2020
    Assignee: Global Life Sciences Solutions Operations UK Ltd
    Inventors: John Richard Nelson, Bing Li
  • Patent number: 10858694
    Abstract: The present invention provides a method of amplifying an RNA molecule in a biological sample by reverse transcription PCR (RT-PCR), wherein the RT-PCR is carried out in a solution comprising a) a polar aprotic solvent; b) a serum albumin; and optionally c) a non-ionic surfactant and/or a betaine.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: December 8, 2020
    Assignee: Global Life Sciences Solutions Operations UK Ltd
    Inventors: Alexander Yarunin, Peter James Tatnell, Kathryn Louise Lamerton, Rebecca Fullerton
  • Patent number: 10822645
    Abstract: The present invention provides a method of amplifying an RNA molecule in a biological sample by reverse transcription PCR (RT-PCR), wherein the RT-PCR is carried out in a solution comprising a polyol, a serum albumin, a non-ionic surfactant and a reducing agent.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: November 3, 2020
    Assignee: Global Life Sciences Solutions Operations UK Ltd
    Inventors: Alexander Yarunin, Peter James Tatnell, Kathryn Louise Lamerton, Rebecca Fullerton