Patents Assigned to GlucoVista Inc.
  • Patent number: 10617337
    Abstract: A substance concentration monitoring method includes inducing a periodic change in a body surface temperature over time using a heating and/or cooling element and yielding a function of temperature that varies with time so as to exhibit a temperature derivative with respect to time that oscillates periodically. Mid-infrared radiation absorbed or emitted from the body is measured while the surface of the body exhibits the oscillating, periodic derivative. The method includes determining a measured value based on the MIR radiation measurements and determining a concentration of a substance in the body based on a correlation with the measured value. A substance concentration monitoring apparatus includes a processor that initiates operations continuously monitoring whether the concentration or the measured value are within a tolerance. The operations further include generating a warning output when the concentration or the measured value is outside the tolerance.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: April 14, 2020
    Assignee: GlucoVista Inc.
    Inventors: Yonatan Gerlitz, Efraim Landa
  • Patent number: 10588552
    Abstract: A substance concentration analysis method includes calculating a difference for the particular time between a first measured amount of mid-infrared (MIR) radiation absorbed by or emitted from a body in a first wavelength and a second measured amount of MIR radiation absorbed by or emitted from the body in a second wavelength, calculating a quotient including a dividend based on the difference divided by a divisor based on a dT/dt value, and calculating the concentration of the substance in the body based on a correlation with the quotient.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: March 17, 2020
    Assignee: GlucoVista Inc.
    Inventors: Yonatan Gerlitz, Efraim Landa, Alexander Ostritsky
  • Patent number: 10376189
    Abstract: A concentration correction system includes an infrared detector and components that produce an aggregate emission of infrared radiation. A mirror assembly includes a mirror and is changeable between a correcting configuration and a measuring configuration. In the correcting configuration, the mirror produces a mirror signal incident on the detector. The mirror assembly also obstructs external body infrared radiation from reaching the detector. In the measuring configuration, the mirror assembly allows the external body infrared radiation onto the detector. A concentration correction method includes receiving external body infrared radiation and simultaneously receiving a first portion of the aggregate emission. A measurement value indicative of concentration is recorded from the detector. A second portion of the aggregate emission reflected with the mirror and produces a mirror signal incident on the detector.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: August 13, 2019
    Assignee: GlucoVista, Inc.
    Inventors: Yonatan Gerlitz, Alexander Ostritsky, Rotem Gerlitz
  • Patent number: 9795329
    Abstract: A system includes a light source and a light detector. The system further includes a first optical system configured to direct a transmitted portion of light onto the detector. The first optical system is further configured to block a scattered portion of the light. The system also includes a second optical system configured to direct the transmitted and scattered portions of the light onto the detector.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: October 24, 2017
    Assignee: GlucoVista Inc.
    Inventor: Yonatan Gerlitz
  • Patent number: 9681832
    Abstract: A measurement apparatus includes a cooling device including two separated, different substances exhibiting an endothermic reaction when combined to decrease a temperature of the cooling device and a contacting mechanism to contact an assay surface with the cooling device. The apparatus includes a temperature measurement device to measure a temperature of the assay surface and an infrared radiation detector to measure infrared radiation emitted or absorbed. A data processor is configured to determine a concentration of a substance in the subject's body using the measured temperature and the infrared radiation. A measurement method includes using the cooling device and decreasing a temperature of the assay surface to a lower temperature, then measuring a temperature of the assay surface during an increase of the temperature. An infrared radiation detector measures infrared radiation emitted from or absorbed by the assay surface during the temperature increase from the lower temperature.
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: June 20, 2017
    Assignee: GlucoVista Inc.
    Inventors: Yonatan Gerlitz, Meir Shitrit
  • Patent number: 8903466
    Abstract: A system for non-invasive measurement of a substance, such as glucose, includes a detector configured to sense radiation and an optical subsystem configured to focus the radiation on a sensitive area of the detector. The system includes one or more temperature sensors attached to one or more of a plurality of elements of the optical subsystem and to the detector and two or more temperature sensors configured to measure two or more respective ambient temperatures. The one or more temperature sensors are configured to measure the temperature of the one or more elements of the optical subsystem and the temperature of the detector. A method of measuring a concentration includes detecting an infrared radiation value, measuring the temperature of the detector, one or more components of the optical system, and two or more ambient temperatures, and correlating the temperatures with calibration parameters to correct the detected infrared radiation value.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 2, 2014
    Assignee: GlucoVista Inc.
    Inventor: Yonatan Gerlitz
  • Publication number: 20130231539
    Abstract: A system for non-invasive measurement of a substance, such as glucose, includes a detector configured to sense radiation and an optical subsystem configured to focus the radiation on a sensitive area of the detector. The system includes one or more temperature sensors attached to one or more of a plurality of elements of the optical subsystem and to the detector and two or more temperature sensors configured to measure two or more respective ambient temperatures. The one or more temperature sensors are configured to measure the temperature of the one or more elements of the optical subsystem and the temperature of the detector. A method of measuring a concentration includes detecting an infrared radiation value, measuring the temperature of the detector, one or more components of the optical system, and two or more ambient temperatures, and correlating the temperatures with calibration parameters to correct the detected infrared radiation value.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 5, 2013
    Applicant: GlucoVista Inc.
    Inventor: Yonatan Gerlitz
  • Patent number: 8364218
    Abstract: A method determines the concentration of a substance in a subject's blood. The method includes measuring an interaction of at least one light beam with a portion of the subject's body. The method further includes calculating a value of an optically-measured parameter indicative of the interaction of the at least one light beam with the substance in the portion of the subject's body. The method further includes measuring values of one or more temperature-indicative parameters corresponding to a temperature of the portion of the subject's body. The method further includes accessing an empirical correlation of the optically-measured parameter and the one or more temperature-indicative parameters to concentrations of the substance in blood. The method further includes obtaining a concentration of the substance in the subject's blood using the empirical correlation. The concentration corresponds to the value of the optically-measured parameter and the values of the one or more temperature-indicative parameters.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: January 29, 2013
    Assignee: GlucoVista, Inc.
    Inventor: Jonathan Gerlitz
  • Patent number: 8219169
    Abstract: A method determines the concentration of a substance in a subject's blood. The method includes noninvasively irradiating an eye with a measurement light beam having a first wavelength and a first power and with a reference light beam having a second wavelength and a second power. The second wavelength is different from the first wavelength. The method further includes measuring at least one of a body temperature of the subject and an ambient temperature of the subject. The method further includes detecting a power of the measurement retro-reflected light beam and detecting a power of the reference retro-reflected light beam. The method further includes calculating a measurement ratio of the detected power of the measurement retro-reflected light beam and the first power and calculating a reference ratio of the detected power of the reference retro-reflected light beam and the second power.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: July 10, 2012
    Assignee: GlucoVista Inc.
    Inventor: Jonathan Gerlitz