Patents Assigned to Glucox AB
  • Methods of treating insulin resistance with an inhibitor of an NAD(P)H oxidase
    Patent number: 7205127
    Abstract: The present invention relates to the use of NAD(P)H oxidase inhibitors to increase cellular uptake of glucose and in the treatment and/or prevention of diseases caused by insulin resistance or diseases related thereto, such as type II diabetes. Specifically, the invention relates to a method for identifying an agent useful for the treatment or prophylaxis of a medical condition associated with elevated levels of blood glucose, the method comprising (i) contacting a candidate agent with a mammalian NAD(P)H oxidase or NAD(P)H oxidase complex; and (ii) determining whether said candidate agent inhibits the biological activities of the NAD(P)H oxidase or NAD(P)H oxidase complex.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: April 17, 2007
    Assignee: Glucox AB
    Inventors: Alvar Grönberg, Per Wikström
  • Identification of agents that increase glucose uptake
    Patent number: 6893833
    Abstract: The present invention relates to the use of NAD(P)H oxidase inhibitors to increase cellular uptake of glucose and in the treatment and/or prevention of diseases caused by insulin resistance or diseases related thereto, such as type II diabetes. Specifically, the invention relates to a method for identifying an agent useful for the treatment or prophylaxis of a medical condition associated with elevated levels of blood glucose, the method comprising (i) contacting a candidate agent with a mammalian NAD(P)H oxidase or NAD(P)H oxidase complex; and (ii) determining whether said candidate agent inhibits the biological activities of the NAD(P)H oxidase or NAD(P)H oxidase complex.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: May 17, 2005
    Assignee: Glucox AB
    Inventors: Alvar Grönberg, Per Wikström