Abstract: Novel core 2 &bgr;-1,6-N-acetylglycosaminyltransferase nucleic acids, polypeptides encoded by the nucleic acids, and uses of the nucleic acids and polypeptides.
Abstract: The invention provides novel core 2 &bgr;-1,6-N-acetylglycosaminyltransferase nucleic acids, and polypeptides encoded by the nucleic acids. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists, and methods for treating disorders associated with the enzyme.
Abstract: Novel core 2 &bgr;-1,6-N-acetylglycosaminyltransferase nucleic acids, polypeptides encoded by the nucleic acids, and uses of the nucleic acids and polypeptides.
Abstract: The invention relates to novel mannosidase inhibitors, processes for their preparation and their use as therapeutic agents. The invention also relates to the use of compounds of the formula II as described herein as prodrugs.
Type:
Grant
Filed:
December 6, 1995
Date of Patent:
June 30, 1998
Assignees:
Mount Sinai Hospital Corporation., GlycoDesign, Inc.
Inventors:
Jeremy Carver, James Wilson Dennis, Rajan Shah