Patents Assigned to Glycominds Ltd.
  • Method for diagnosing multiple sclerosis
    Patent number: 8216791
    Abstract: Disclosed is a method for diagnosing and prognosing multiple sclerosis and more particularly to a method for diagnosing and prognosing multiple sclerosis by measuring levels of antibodies. The levels of IgM-type anti-Glc(?1,2)Glc(?) or Glc(?1,3)Glc(?) or Glc(?1,6)Glc(?) antibodies in serum act as diagnostic markers for MS disease and as prognostic biomarkers for the conversion of CIS patients suggestive of MS to clinically definite MS (CDMS) within 24 months.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: July 10, 2012
    Assignee: Glycominds Ltd.
    Inventors: Nir Dotan, Avinoam Dukler
  • Immunoassay reagent compositions for diagnosing multiple sclerosis
    Patent number: 8129128
    Abstract: This application is related to immunoassay reagent compositions comprising a glycan reagent for diagnosing multiple sclerosis.
    Type: Grant
    Filed: August 5, 2009
    Date of Patent: March 6, 2012
    Assignee: Glycominds, Ltd.
    Inventors: Nir Dotan, Avinoam Dukler, Mikael Schwarz
  • Method for evaluating risk in multiple sclerosis
    Patent number: 8048639
    Abstract: The invention relates to methods and reagents for diagnosing and assessing the prognosis of multiple sclerosis.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: November 1, 2011
    Assignee: Glycominds Ltd.
    Inventors: Nir Dotan, Avinoam Dukler, Jennifer Yarden
  • Method For Diagnosing Multiple Sclerosis
    Publication number: 20110092383
    Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.
    Type: Application
    Filed: October 14, 2010
    Publication date: April 21, 2011
    Applicant: Glycominds, LTD
    Inventors: Nir Dotan, Avinoam Dukler
  • Method for diagnosing multiple sclerosis
    Patent number: 7906291
    Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: March 15, 2011
    Assignee: Glycominds Ltd.
    Inventors: Nir Dotan, Avinoam Dukler
  • Method for Diagnosing Prognosing Inflammatory Bowel Disease and Crohn's Disease
    Publication number: 20100254971
    Abstract: Disclosed are methods for diagnosing and prognosing Inflammatory Bowel disease or Crohn's disease (CD) by measuring levels of antibodies to glycans in a biological sample.
    Type: Application
    Filed: October 26, 2009
    Publication date: October 7, 2010
    Applicant: Glycominds LTD.
    Inventors: Nir Dotan, Avinoam Dukler, Rom T. Altstock
  • Method for Evaluating Risk in Multiple Sclerosis
    Publication number: 20100227337
    Abstract: The invention relates to methods and reagents for diagnosing and assessing the prognosis of multiple sclerosis.
    Type: Application
    Filed: February 11, 2010
    Publication date: September 9, 2010
    Applicant: Glycominds LTD.
    Inventors: Nir Dotan, Avinoam Dukler, Jennifer Yarden
  • Method for Diagnosing Multiple Sclerosis
    Publication number: 20100159472
    Abstract: Disclosed is a method for diagnosing and prognosing multiple sclerosis and more particularly to a method for diagnosing and prognosing multiple sclerosis by measuring levels of antibodies. The levels of IgM-type anti-Glc(?1,2)Glc(?) or Glc(?1,3)Glc(?) or Glc(?1,6)Glc(?) antibodies in serum act as diagnostic markers for MS disease and as prognostic biomarkers for the conversion of CIS patients suggestive of MS to clinically definite MS (CDMS) within 24 months.
    Type: Application
    Filed: September 9, 2009
    Publication date: June 24, 2010
    Applicant: Glycominds, LTD
    Inventors: Nir Dotan, Avinoam Dukler
  • Method for Diagnosing Diseases Based on Levels of Anti-Glycan Antibodies
    Publication number: 20100099124
    Abstract: Disclosed are methods for diagnosing Crohn's disease (CD) or anti-phospholipid syndrome by measuring levels of antibodies to glycans in a biological sample.
    Type: Application
    Filed: September 21, 2009
    Publication date: April 22, 2010
    Applicant: Glycominds, LTD
    Inventors: Nir Dotan, Avinoam Dukler
  • Method for Diagnosing Multiple Sclerosis
    Publication number: 20100081160
    Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.
    Type: Application
    Filed: May 22, 2009
    Publication date: April 1, 2010
    Applicant: Glycominds LTD.
    Inventors: Nir Dotan, Avinoam Dukler, Mikael Schwarz, Ari Gargir
  • Method for Diagnosing Multiple Sclerosis
    Publication number: 20090291456
    Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.
    Type: Application
    Filed: August 5, 2009
    Publication date: November 26, 2009
    Applicant: Glycominds, LTD
    Inventors: Nir Dotan, Avinoam Dukler, Mikael Scwartz
  • Method for diagnosing and prognosing inflammatory bowel disease and crohn's disease
    Patent number: 7608414
    Abstract: Disclosed are methods for diagnosing and prognosing Inflammatory Bowel disease or Crohn's disease (CD) by measuring levels of antibodies to glycans in a biological sample.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: October 27, 2009
    Assignee: Glycominds, Ltd
    Inventors: Nir Dotan, Avinoam Dukler, Rom T. Altstock
  • Method for diagnosing diseases based on levels of anti-glycan antibodies
    Patent number: 7592150
    Abstract: Disclosed are methods for diagnosing Crohn's disease (CD) or anti-phospholipid syndrome by measuring levels of antibodies to glycans in a biological sample.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: September 22, 2009
    Assignee: Glycominds, Ltd
    Inventors: Nir Dotan, Avinoam Dukler
  • Method for diagnosing multiple sclerosis
    Patent number: 7572592
    Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.
    Type: Grant
    Filed: January 31, 2005
    Date of Patent: August 11, 2009
    Assignee: Glycominds Ltd
    Inventors: Nir Dotan, Avinoam Dukler, Mikael Scwartz
  • Method for diagnosing multiple sclerosis
    Patent number: 7537900
    Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.
    Type: Grant
    Filed: August 4, 2003
    Date of Patent: May 26, 2009
    Assignee: Glycominds Ltd.
    Inventors: Nir Dotan, Avinoam Dukler, Mikael Schwarz, Ari Gargir
  • Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
    Publication number: 20080085838
    Abstract: A combinatorial complex carbohydrate library is provided and including a plurality of addressable complex carbohydrate structures.
    Type: Application
    Filed: September 5, 2007
    Publication date: April 10, 2008
    Applicant: Glycominds Ltd.
    Inventors: Avinoam Dukler, Nir Dotan
  • Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
    Patent number: 6994966
    Abstract: The present invention provides methods of utilizing a complex carbohydrate library which includes a plurality of complex carbohydrate structures each being attached to a specific site of a solid support such as a platform for screening and isolating complex carbohydrate structures capable of specifically and uniquely binding with an entity such as a polypeptide.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: February 7, 2006
    Assignee: Glycominds Ltd.
    Inventors: Avinoam Dukler, Nir Dotan
  • Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
    Patent number: 6972172
    Abstract: The present invention provides a complex carbohydrate library which includes a plurality of complex carbohydrate structures each being attached to a specific site of a solid support such as a platform, thereby making each of the plurality of complex carbohydrate structures uniquely addressable. The addressable nature of the complex carbohydrate library of the present invention makes it particularly suitable for screening and isolating molecules that bind specifically and uniquely to complex carbohydrate structures associated with various disorders and conditions, thus enabling identification of new drugs candidates.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: December 6, 2005
    Assignee: Glycominds Ltd.
    Inventors: Avinoam Dukler, Nir Dotan
  • Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
    Publication number: 20020127599
    Abstract: A combinatorial complex carbohydrate library is provided and including a plurality of addressable complex carbohydrate structures.
    Type: Application
    Filed: May 21, 2001
    Publication date: September 12, 2002
    Applicant: Glycominds Ltd.
    Inventors: Avinoam Dukler, Nir Dotan
  • Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
    Publication number: 20020098513
    Abstract: A combinatorial complex carbohydrate library is provided and including a plurality of addressable complex carbohydrate structures.
    Type: Application
    Filed: May 21, 2001
    Publication date: July 25, 2002
    Applicant: Glycominds Ltd.
    Inventors: Avinoam Dukler, Nir Dotan