Abstract: A conjugate is disclosed. The conjugate may be represented by Formula I: [D-G-L]n-T Formula I wherein D is a payload molecule; O is an oxygen atom of said payload molecule; T is a targeting unit capable of binding a target molecule, cell and/or tissue; and n is at least 1.
Type:
Application
Filed:
December 18, 2020
Publication date:
February 9, 2023
Applicant:
Glykos Biomedical OY
Inventors:
Tero SATOMAA, Juhani SAARINEN, Jari HELIN, Olli AITIO, Henna PYNNĂ–NEN
Abstract: A conjugate is disclosed. The conjugate may comprise a targeting unit for delivery to a tumour, and a glycosylation inhibitor for inhibiting glycosylation in the tumour, thereby decreasing the immunosuppressive activity of the tumour. The glycosylation inhibitor may be conjugated to the targeting unit.
Type:
Application
Filed:
June 19, 2019
Publication date:
December 30, 2021
Applicant:
GLYKOS BIOMEDICAL OY
Inventors:
Juhani SAARINEN, Tero SATOMAA, Olli AITIO
Abstract: A conjugate is disclosed. The conjugate may comprise a targeting unit for delivery to a target tissue, and a Galectin inhibitor for inhibiting Galectin interaction within the target tissue, wherein the Galectin inhibitor is conjugated to the targeting unit.