Patents Assigned to Glyphic Biotechnologies, Inc.
  • Protein sequencing via coupling of polymerizable molecules
    Patent number: 12259393
    Abstract: “The present disclosure provides methods and systems for sequencing proteins. One or more methods disclosed herein may use linkers having an amino acid-reactive group and an additional reactive moiety that may be used to couple a polymerizable molecule. The linker may couple to a polymerizable molecule and an amino acid of a peptide and a capture moiety via the polymerizable molecule, followed by cleavage of the amino acid from the peptide. Further processing and analysis may be conducted using, for example, nanopores or nanogaps.
    Type: Grant
    Filed: April 4, 2024
    Date of Patent: March 25, 2025
    Assignee: Glyphic Biotechnologies, Inc.
    Inventors: Asmamaw Wassie, Daniel Masao Estandian, Andrew John Price, Boyang Hua, Joshua Young Cynming Yang, David Dodd, Gerardo Fabian Delgado, Elaine Jean Su
  • Protein sequencing via coupling of polymerizable molecules
    Patent number: 12259394
    Abstract: The present disclosure provides methods and systems for sequencing proteins. One or more methods disclosed herein may use linkers having an amino acid-reactive group and an additional reactive moiety that may be used to couple a polymerizable molecule. The linker may couple to a polymerizable molecule and an amino acid of a peptide and a capture moiety via the polymerizable molecule, followed by cleavage of the amino acid from the peptide. Further processing and analysis may be conducted using, for example, nanopores or nanogaps.
    Type: Grant
    Filed: April 4, 2024
    Date of Patent: March 25, 2025
    Assignee: Glyphic Biotechnologies, Inc.
    Inventors: Asmamaw Wassie, Daniel Masao Estandian, Andrew John Price, Boyang Hua, Joshua Young Cynming Yang, David Dodd, Gerardo Fabian Delgado, Elaine Jean Su