Abstract: Patch-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes and other agents into the tissues of the living body. The patch devices provide an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only, electroporation only, or combined inontophoresis and electroporation. The two procedures may be applied sequentially in any order without removing or repositioning the patch.
Type:
Grant
Filed:
July 22, 2002
Date of Patent:
December 9, 2003
Assignee:
GMP Drug Delivery, Inc.
Inventors:
Neville Crawford, Charles L. Brown, III
Abstract: Patch-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the tissues of the living body. The patch devices provide an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only, electroporation only, or combined iontophoresis and electroporation. The two procedures may be applied sequentially in any order without removing or repositioning the patch.
Abstract: Patch-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the tissues of the living body. The patch devices provide an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only, electroporation only, or combined iontophoresis and electroporation. The two procedures may be applied sequentially in any order without removing or repositioning the patch.
Type:
Grant
Filed:
February 10, 2000
Date of Patent:
July 23, 2002
Assignee:
GMP Drug Delivery, Inc.
Inventors:
Charles L. Brown, III, Neville Crawford