Patents Assigned to GMP-ORPHAN SA
  • CRYSTALLINE FORM OF TRIETHYLENETETRAMINE TETRAHYDROCHLORIDE AND ITS PHARMACEUTICAL USE
    Publication number: 20200392068
    Abstract: The present invention describes a new crystalline form of triethylenetetramine tetrachloride which has improved room temperature stability over known forms and over the dichloride salt. The new crystalline form is characterised by having peaks in an XRPD spectrum at 22.9, 25.4, 25.8, 26.6, 34.6 and 35.3±0.1°2? and Raman shifts 943, 1173, 1527 and 1612±5 cm?1. The crystalline form of triethylenetetramine tetrachloride is useful in the treatment of Wilson's disease.
    Type: Application
    Filed: June 30, 2020
    Publication date: December 17, 2020
    Applicant: GMP-ORPHAN SA
    Inventors: Timothy James Morley, Ronnie Maxwell Lawrence, Naseem Amin