Abstract: The present invention provides a process for the preparation of tablets comprising S-adenosylmethionine and/or a pharmaceutically and/or dietarily acceptable derivative thereof by blending that active component with specified additives, compressing the blend, followed by coating.
Abstract: There is disclosed a fermentation process for producing glutathione which comprises (a) the obtainment of a biomass pre-culture by pre-cultivating, in aerobic conditions, a strain of a glutathione producing yeast wherein the glutathione content per biomass unit is higher than 1.2% w/w; (b) the cultivation, in aerobic conditions, of the resulting biomass pre-culture such that the resulting biomass density is higher than 50 g/l; (c) the activation of the cultured biomass; and (d) the recovery of the cultured biomass, extracting glutathione at a pH equal to or lower than 6 and purifying the resulting glutathione. The process allows to obtain glutathione with high yields and relatively low costs.
Type:
Grant
Filed:
July 1, 2003
Date of Patent:
June 7, 2005
Assignee:
Gnosis Srl
Inventors:
Alberto Benedetti, Enrico Giuseppe Roberto Berardi, Matilde Manzoni, Marina Nichele, Hermes Pagani, Manuela Rollini
Abstract: There is disclosed a fermentation process for producing glutathione which comprises (a) the obtainment of a biomass pre-culture by pre-cultivating, in aerobic conditions, a strain of a glutathione producing yeast wherein the glutathione content per biomass unit is higher than 1.2% w/w; (b) the cultivation, in aerobic conditions, of the resulting biomass pre-culture such that the resulting biomass density is higher than 50 g/l; (c) the activation of the cultured biomass; and (d) the recovery of the cultured biomass, extracting glutathione at a pH equal to or lower than 6 and purifying the resulting glutathione. The process allows to obtain glutathione with high yields and relatively low costs.
Abstract: By carrying out the fermentation of Streptomyces avermitilis ATCC 55278, a dried mycelium is obtained which, orally administered to animals, particularly to ovines, has an antiparasitic activity.
Type:
Grant
Filed:
April 30, 1993
Date of Patent:
December 27, 1994
Assignees:
Gnosis srl, Euroresearch srl
Inventors:
M. Leonardo Cappelletti, Giacomo Lucarelli, Giuseppe Mearelli