Abstract: The present disclosure relates to supports comprising a substrate and a plurality of sample spots on the surface of the support, wherein the sample spots are spatially separated from another by the substrate, and wherein a single biomolecule is immobilized on at least 2 separate sample spots.

Abstract: The present disclosure relates to the analysis of molecular events as observed by irradiating a sample with a primary electromagnetic radiation, and detecting secondary electromagnetic radiation emitted by the sample induced by said primary electromagnetic radiation, wherein the sample is irradiated by a primary electromagnetic radiation and wherein at least one characteristic of said primary electromagnetic radiation is altered several times during the time period of the event.

Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.

Abstract: The invention relates to a process and a device for analyzing single molecules, particularly to the parallel analysis of a plurality of single molecules. It is suitable for detecting interactions, e.g. binding between single molecules and/or reactions, e.g. elongation or degradation of single molecules. Particularly, the process of the invention relates to the sequencing of single nucleic acid molecules. The single molecule to be analyzed is present in free form, i.e. dissolved or suspended in a liquid medium, within a reaction space formed around the sample spot. According to the present invention, an electrical field is applied across the reaction space, whereby a concentration of single molecules, at the sample spots is effected.

Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.

Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.

Abstract: The invention relates to a process and a device for analyzing single molecules, particularly to the parallel analysis of a plurality of single molecules. It is suitable for detecting interactions, e.g. binding between single molecules and/or reactions, e.g. elongation or degradation of single molecules. Particularly, the process of the invention relates to the sequencing of single nucleic acid molecules. The single molecule to be analyzed is present in free form, i.e. dissolved or suspended in a liquid medium, within a reaction space formed around the sample spot. According to the present invention, an electrical field is applied across the reaction space, whereby a concentration of single molecules, at the sample spots is effected.

Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.

Abstract: The invention relates to a process and a device for analysing single molecules, particularly to the parallel analysis of a plurality of single molecules. It is suitable for detecting interactions, e.g. binding between single molecules and/or reactions, e.g. elongation or degradation of single molecules. Particularly, the process of the invention relates to the sequencing of single nucleic acid molecules. The single molecule to be analysed is present in free form, i.e. dissolved or suspended in a liquid medium, within a reaction space formed around the sample spot. According to the present invention, an electrical field is applied across the reaction space, whereby a concentration of single molecules, at the sample spots is effected.

Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.

Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.

Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.

Abstract: The present invention relates to 5?-3?-bifluorophore-labelled probes for detecting analytes, in particular nucleic acids, in particular for confocal fluorescence spectroscopy.