Abstract: Chemotherapeutic antineoplastic method comprising administration of an effective amount of an antineoplastic agent in conjunction with an effective amount of a ?-1,3 glucan.

Abstract: The invention relates to a device of the type adapted to deliver fluids, notably medicaments, under pressure. The device comprises a container 1 of variable volume in the form or shape of a pouch or flexible receptacle of generally cylindrical shape with longitudinal pleats 2 containing the fluid under pressure to be delivered and equipped with an actuator C permitting to open a valve 15a, 15b to enable the delivery of said fluid, the whole being located inside a container 4 capable of resisting to an elevated internal pressure, the internal volume of the latter container comprised between its wall and the container of variable volume being filled with a neutral gas under a pressure sufficient to exert on the container of variable volume a pneumatic constraint sufficient to permit the delivery of the therein contained fluid when the above-said valve permitting said delivery is operated by the aforementioned actuator C.

Abstract: The invention concerns the use for preparing a medicine for treating inflammatory diseases induced by non-specific inflammatory responses, that is antigen-independent, of a laminarin sulphate, having a degree of sulphation not less than 1.9 and preferably between 2 and 2.5 degree of polymerization identical to that of the natural molecule, that is 20 to 30.

Abstract: The invention concerns endofucanases suitable for preparing fuco-oligosaccharides by enzymatic hydrolysis of fucanes. It also concerns a bacterium producing endofucanases and the preparation of said enzyme from the bacterium. It further concerns endofucanase genes and it finally concerns the use said fuco-oligosaccharides for plant protection.

Abstract: The invention relates to a method for the stimulation of the reactions of natural defence of agronomically useful and of decorative plants, characterized by the fact that there is applied on the plants to be treated an aqueous composition comprising an efficient concentration in sulfate of ? 1-3 glucan and more particularly a concentration of at least 1 mg/l, preferably of at least 5 mg/l, and still more preferably of at least 10 mg/l in laminarin sulfate, whose degree of sulfatation is higher than or equal to 1.9, preferably from 2 to 2.5, the said composition being applied to the culture or crop to be treated in an amount sufficient to provide per hectare an efficient amount of sulfate of ? 1-3 glucan, and in the case of laminarin sulfate in an amount sufficient to provide from 0.4 to 4 g of laminarin sulfate per hectare.

Abstract: Treatment for preventing and limiting the release of the chemical mediators which are responsible of the starting of cutaneous inflammatory phenomena comprising administration to a patient of hypoosmotic saline solutions.

Abstract: The present invention relates to genes which code for glycosyl hydrolases having an HCA score with the iota-carrageenase of Alteromonas fortis which is greater than or equal to 65% over the domain extending between amino acids 164 and 311 of the protein sequence SEQ ID No. 2 of said iota-carrageenase, and to genes which code for glycosyl hydrolases having an HCA score with the kappa-carrageenase of Alteromonas carrageenovora which is greater than or equal to 75% over the domain extending between amino acids 117 and 262 of the protein sequence SEQ ID No. 6 of said kappa-carrageenase.

Abstract: The invention concerns a medicine comprising, as active principle, an efficient quantity of at least an oligosaccharide substance capable of modulating apoptosis dysfunction which is capable of modifying apoptosis dysfunctions said substance being selected from the group consisting of oligosaccharides which are derived, by enzymatic or chemical process, from the polymers of the group comprising (1→3)-&bgr;-glucans which optionally comprise (1→6)-&bgr;-branching, and oligosaccharides which are derived, by enzymatic or chemical process, from sulfated galactans, it also concerns a method for treating apoptosis dysfunction.

Abstract: The invention concerns the use of iso-osmotic saline solutions, in particular obtained from sea water, to obtain a medicine for cerumenolytic treatment.

Abstract: Therapeutical method comprising administration to a patient of an effective amount of especially soluble laminarin for the treatment of tumors and more generally of cancers of the group comprising breast cancer, lung cancer, oesophagus cancer, stomach cancer, intestine and colon cancers, and for the treatment of viral, bacterial and fungal diseases as well as diseases related to immunostimulant deficiencies of human beings and warm-blood animals.

Abstract: The invention relates to the novel Cytophaga drobachiensis strain deposited in the DSMZ Collection (Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (German Collection of Microorganisms and Cell Cultures)) on May 8, 1998 under the number DSM 12170, the agaA gene coding for a &bgr;-agarase and having SEQ ID No. 1, the agaB gene coding for a &bgr;-agarase and having SEQ ID No. 3, said genes coding for a &bgr;-agarase of Cytophaga drobachiensis DSM 12170, and the specific nucleic acid sequence of the agaA gene coding for a specific peptide fragment AgaA′ which has conserved &bgr;-agarase activity, and having SEQ ID No. 5, as well as the protein AgaA of C. drobachiensis DSM 12170 having SEQ ID No. 2, the protein AgaB of C. drobachiensis DSM 12170 having SEQ ID No. 4 and said peptide fragment AgaA′ of C. drobachiensis DSM 12170 having SEQ ID No. 6.

Abstract: The invention concerns the use of iso-osmotic saline solutions in particular obtained from sea water, to obtain a medicine designed for a treatment preventing and limiting the release of chemical mediators responsible for causing inflammatory phenomena in the human respiratory tracts.

Abstract: The present invention provides a method to potentiate and stimulate natural defensive reactions of plants to a pathogenic agent. The method comprises application to plants of a composition comprising an effective amount of one or more oligo &bgr; 1-3 glucans composed of 3 to 250 monosaccharide units and a vehicle, wherein the effective amount of oligo &bgr; 1-3 glucans in the composition does not directly stimulate natural defensive reactions of plants when the pathogenic agent is absent.

Abstract: The present invention relates to genes which code for glycosyl hydrolases having an HCA score with the iota-carrageenase of Alteromonas fortis which is greater than or equal to 65% over the domain extending between amino acids 164 and 311 of the protein sequence SEQ ID No. 2 of said iota-carrageenase, and to genes which code for glycosyl hydrolases having an HCA score with the kappa-carrageenase of Alteromonas carrageenovora which is greater than or equal to 75% over the domain extending between amino acids 117 and 262 of the protein sequence SEQ ID No. 6 of said kappa-carrageenase.

Abstract: Composition for application, in particular to leaves, comprising an excipient, the conventional constituents of compositions for application, in particular to leaves, and an active ingredient, characterized by the fact that the active ingredient is constituted by at least one phytosanitary product capable of stimulating the germination of pollen grains, selected from the group comprising: oligosaccharides having a degree of polymerization up to 10 and comprising up to 10, preferably up to 5 and, even more preferably, two glucidic units linked by &bgr;1-3, &bgr;1-4 et &agr;1-3, particularly those of the group comprising laminaribiose, cellobiose, nigerose, laminaritriose, laminaritetraose and laminaripentaose, derivatives of the above oligosaccharides substituted on the free anomeric carbon atom or on all the carbon atoms having a free hydroxide by a radical selected from the group comprising: C1 to C5 alkyl radicals, preferably the methyl radical, C1 to C5 acyl radicals, preferably the acetyl radical, ar

Abstract: The use of aluminium chloride as a resveratrol synthesis elicitor in crop plants and edible products thereof, particularly in the field of vine and grape growing as well as in the production of grape juice and wine, is disclosed.

Abstract: A cosmetic or pharmaceutical, particularly dermatological, composition including an effective amount of laminarin or laminarin-derived oligosaccharides as the active ingredient. It has been discovered that laminarin, oligosaccharides derived therefrom and compositions containing same have stimulating, regenerating, conditioning and energising effects on human dermis fibroblasts and human epidermis keratinocytes. Said composition is useful in cosmetics and pharmacology.

Abstract: The present invention relates to the use of laminarin as a seed germination and plant growth accelerator.The invention applies to the field of agriculture for treatments via the leaves or to the soil.

Abstract: A method for improving the germination of seeds or the growth of bulbs in which, prior to planting, the seeds or bulbs are placed into contact with gaseous ozone and the residual moisture content of the seeds or bulbs is adjusted before or simultaneously with the ozone contact to a value in the range of 5 to 60% by weight. The seeds or bulbs produced thereby are suitable for storage without any additional drying step.

Abstract: The present invention relates to a new physiological product extracted from algae and plants (e.g. artichokes), the process and apparatus used in its preparation by a combination of cryocomminution and molecular milling followed by ultra-decantation and ultra-filtration to obtain a sterile microburst product are described.