Abstract: A quick connection device for an aseptic bag may include: a mouth; a mouth sealing cover; and a mouth connection piece. To prevent flow through the mouth, the mouth sealing cover is mountable at the mouth. To allow the flow through the mouth, the mouth connection piece is mountable at the mouth. The mouth can include arc-shaped grooves on an upper surface of the mouth. When the mouth sealing cover is mounted at the mouth, a lower surface of the mouth can be sealed with laminate compound film. The mouth sealing cover can include arc-shaped heaves on two sides. When the mouth sealing cover is mounted at the mouth, the arc-shaped heaves can be fastened with the arc-shaped grooves on the upper surface of the mouth for sealing.