Patents Assigned to GOLGI NEUROSCIENCES S.R.L.
  • Bicyclic CX3CR1 receptor agonists
    Patent number: 11958839
    Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.
    Type: Grant
    Filed: September 22, 2021
    Date of Patent: April 16, 2024
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, GOLGI NEUROSCIENCES, S.R.L.
    Inventors: Paolo Pevarello, William J. Ray, Mary Hamby, Yaima Luzardo Lightfoot, Philip Jones, Russell Thomas, Chiara Liberati, Domenica Torino, Valentina Cusano, Francesco Piscitelli, Ali Munaim Yousif, Silvia Bovolenta
  • Substituted pyrazoles FFA4/GPR120 receptor agonists
    Patent number: 11597702
    Abstract: Disclosed are compounds of formula (I) or a pharmaceutically acceptable salt thereof: These compounds have FFA4/GPR120 receptor (FFA4) agonistic properties. Also disclosed are pharmaceutical compositions including these compounds, chemical processes for preparing them and their use in the treatment or prophylaxis of diseases associated with FFA4 receptor activity in animals, in particular humans.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: March 7, 2023
    Assignee: GOLGI NEUROSCIENCES S.R.L.
    Inventors: Domenica Torino, Francesco Piscitelli, Valentina Cusano, Rocco Vitalone, Andrew Griffin, Russell Thomas, Paolo Pevarello, Ali Munaim Yousif