Abstract: A measurement device for a human respiratory system function comprises a respiration measurement device (20). The respiration measurement device (20) receives a respiratory air flow and senses the respiratory air flow to generate a set of sensing signals, and performs calculation according to the sensing signals to generate a human respiratory system parameter, the sensing signals comprising at least an absolute pressure of the respiratory air flow. The respiration measurement device (20) comprises a respiration measurement channel (21). The absolute pressure generated by a respiratory air flow of a user in the respiration measurement channel (21) that is in a single-end sealed state is measured. The absolute pressure corresponds to the pressure in the lung of the user.