Abstract: Disclosed is a DNA chip (or DNA microarray) on which probes complementarily binding to the nucleic acids of 44 types of HPV, which is the main cause of cervical cancer and the most common cause of sexually transmitted diseases, are spotted, a genotyping kit including same and a genotyping method using same. In accordance with the present disclosure, all the 44 types of HPV invading the genitalia can be detected and coinfection by more than one type of HPV can be diagnosed accurately. The sensitivity and specificity of HPV genotyping is close to 100% and a number of samples can be tested quickly. The present disclosure is very useful in predicting cervical cancer and precancerous lesions.
Abstract: The present invention relates to mutation genes of the AQP (aquaporin), a method for detecting cancer using mutations and expressions of the AQP and a DNA chip possessing oligonucleotides of mutated AQP base sequence. In case of the present method for detecting cancer and DNA chip using the AQP's mutations and expressions, it is highly accurate, rapid and effective in cancer diagnosis.
Type:
Grant
Filed:
June 4, 2007
Date of Patent:
September 6, 2011
Assignee:
Goodgene, Inc.
Inventors:
Woo-chul Moon, Chul-so Moon, Young-ho Moon, Byung-gu Kim, Dong-hwan Kim, Chan-jae Shin, Tae-han Um, Hwa-su Kim, Mi-kyung Song, Hyeung-jae Kim, Seok-beom Song
Abstract: The present invention relates to cationic lipids, methods for preparing some and methods for effectively transporting anionic molecular substances into cell by using said cationic lipids. The present lipids are compatible to gene therapy due to their stability and highly transporting effects.
Type:
Grant
Filed:
September 21, 2001
Date of Patent:
June 23, 2009
Assignee:
Goodgene, Inc.
Inventors:
Woo-chul Moon, Chul-so Moon, Byung-gu Kim, Chan-jae Shin, Hyeung-jae Kim, Young-ho Moon, Dong-hwan Kim, Tae-han Um, Hwa-su Kim, Mi-kyung Song, Seok-beom Song
Abstract: The present invention relates to mutation genes of the AQP(aquaporin), a method for detecting cancer using mutations and expressions of the AQP and a DNA chip possessing oligonucleotides of mutated AQP base sequence. In case of the present method for detecting cancer and DNA chip using the AQP's mutations and expressions, it is highly accurate, rapid and effective in cancer diagnosis.
Type:
Grant
Filed:
September 10, 2001
Date of Patent:
December 30, 2008
Assignee:
Goodgene, Inc.
Inventors:
Woo-chul Moon, Chul-so Moon, Young-ho Moon, Byung-gu Kim, Dong-hwan Kim, Chan-jae Shin, Tae-han Um, Hwa-su Kim, Mi-kyung Song, Hyeung-jae Kim, Seok-beom Song