Patents Assigned to GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY
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Patent number: 11046579Abstract: Disclosed herein is a method of providing a structure having two electrodes connected by nanowires, exposing the structure to an analyte that can adsorb onto the nanowires, and passing an electrical current through the nanowires to heat the nanowires to desorb the analyte. Also disclosed herein is an apparatus having the above structure; a current source electrically connected to the electrodes, and a detector to detect the analyte.Type: GrantFiled: December 9, 2019Date of Patent: June 29, 2021Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Braden C. Giordano, Pehr E. Pehrsson, Kevin J. Johnson, Daniel Ratchford, Christopher Field, Junghoon Yeom
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Patent number: 11050405Abstract: A micromechanical vibrasolator isolates vibration of a micromechanical resonator and includes: phononic bandgap mirrors, monophones connected serially; phonophore arms in an alternating sequence of phonophore arm-monophone-phonophore arm; abutments in acoustic communication with the phononic bandgap mirrors; wherein the micromechanical resonator is interposed between the phononic bandgap mirrors with phononic bandgap mirror arranged in parallel on opposing sides of the micromechanical resonator arranged perpendicular to a direction of vibration of an in-plane vibrational mode of the micromechanical resonator.Type: GrantFiled: April 5, 2019Date of Patent: June 29, 2021Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCEInventors: Jason J. Gorman, Vikrant J. Gokhale
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Patent number: 11045558Abstract: Methods for treating a human subject who has X-linked Retinitis Pigmentosa (XLRP) or another clinically-defined ophthalmological condition due to a loss-of-function mutation in the gene encoding the retinitis pigmentosa GTPase regulator (RPGR) protein, the method comprising administering to the subject a nucleic acid comprising an adeno-associated viral vector comprising an abbreviated human RPGR cDNA.Type: GrantFiled: June 10, 2019Date of Patent: June 29, 2021Assignees: Massachusetts Eye & Ear Infirmary, UCL Business Ltd., The Government of the United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Michael A. Sandberg, Basil Pawlyk, Alan Finlay Wright, Xinhua Shu, Tiansen Li, Robin Ali
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Publication number: 20210187447Abstract: An article having a nanoporous membrane and a nanoporous graphene sheet layered on the nanoporous membrane. A method of: depositing a layer of a diblock copolymer onto a graphene sheet, and etching a minor phase of the diblock copolymer and a portion of the graphene in contact with the minor phase to form a nanoporous article having a nanoporous graphene sheet and a nanoporous layer of a polymer. A method of: depositing a hexaiodo-substituted macrocycle onto a substrate having a Ag(111) surface; coupling the macrocycle to form a nanoporous graphene sheet; layering the graphene sheet and substrate onto a nanoporous membrane with the graphene sheet in contact with the nanoporous membrane; and etching away the substrate.Type: ApplicationFiled: March 4, 2021Publication date: June 24, 2021Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Manoj K. Kolel-Veetil, Paul E. Sheehan
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Publication number: 20210188716Abstract: Disclosed is a composition having nanoparticles or particles of a refractory metal, a refractory metal hydride, a refractory metal carbide, a refractory metal nitride, or a refractory metal boride, an organic compound consisting of carbon and hydrogen, and a nitrogenous compound consisting of carbon, nitrogen, and hydrogen. The composition, optionally containing the nitrogenous compound, is milled, cured to form a thermoset, compacted into a geometric shape, and heated in a nitrogen atmosphere at a temperature that forms a nanoparticle composition comprising nanoparticles of metal nitride and optionally metal carbide. The nanoparticles have a uniform distribution of the nitride or carbide.Type: ApplicationFiled: March 3, 2021Publication date: June 24, 2021Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Matthew Laskoski, Boris Dyatkin, Teddy M. Keller
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Publication number: 20210188732Abstract: An explosive sheet simulant that uses an ethylene vinyl acetate polymer combined with a mixture of a boron carbide and iron oxide for X-ray attenuating properties, and components of the mixture selected for predetermined flexural modulus combined with particle density, effective atomic number, X-ray transmission properties, or millimeter wave properties.Type: ApplicationFiled: March 5, 2021Publication date: June 24, 2021Applicant: The Government of the United States of America, as represented by the Secretary of Homeland SecurityInventors: Michael Brogden, Steve Duffy
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Patent number: 11041008Abstract: The present invention provides method for promoting the maturation and export of T cells from thymic tissue by contacting the thymic tissue with supraphysiological levels of interleukin (IL)-15. The present invention also provides methods for preventing, alleviating, reducing, and/or inhibiting lymphopenia or peripheral depletion of lymphocytes in a patient in need thereof by administering to the patient IL-15.Type: GrantFiled: September 6, 2018Date of Patent: June 22, 2021Assignee: The Government of the United States of America as Represented by The Secretary of the Department of Health and Human ServicesInventors: Cristina Bergamaschi, Barbara K. Felber, George N. Pavlakis, Antonio Valentin
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Patent number: 11043785Abstract: Methods for synthesizing fibers having nanoparticles therein are provided, as well as preforms and fibers incorporating nanoparticles. The nanoparticles may include one or more rare earth ions selected based on fluorescence at eye-safer wavelengths, surrounded by a low-phonon energy host. Nanoparticles that are not doped with rare earth ions may also be included as a co-dopant to help increase solubility of nanoparticles doped with rare earth ions in the silica matrix. The nanoparticles may be incorporated into a preform, which is then drawn to form fiber. The fibers may beneficially be incorporated into lasers and amplifiers that operate at eye safer wavelengths. Lasers and amplifiers incorporating the fibers may also beneficially exhibit reduced Stimulated Brillouin Scattering.Type: GrantFiled: October 13, 2017Date of Patent: June 22, 2021Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Colin C. Baker, Edward J. Friebele, Woohong Kim, L. Brandon Shaw, Jasbinder S. Sanghera
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Patent number: 11044549Abstract: Supercoupling power dividers are provided, in which acoustic impedance at an acoustic input port matches the combined acoustic impedance at two or more acoustic output ports, and the phase of the input signal matches the combined phases of the two or more acoustic output ports. Methods for achieving impedance matching using a uniform-phase acoustic power divider are also provided. The devices and methods achieve acoustic supercoupling without requiring embedded membranes or resonators.Type: GrantFiled: December 3, 2019Date of Patent: June 22, 2021Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Matthew S. Byrne, Hussein Esfahlani, Andrea Alu
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Publication number: 20210181542Abstract: A tunable spectral filter comprising a phase change material is incorporated into a multilayered dielectric structure. The dielectric permittivity, and thus the filter properties, of the structure can be modified by producing a change in the phase change material, e.g., causing a metal-insulator transition. By controllably causing such a change in the dielectric permittivity of the phase change material, the spectral transmittance and reflectance of the structure, and thus its filter properties, can be modified to provide a predetermined transmittance or reflectance of electromagnetic radiation incident on the structure. In preferred embodiments, the phase change material layer is a vanadium dioxide (VO2) film formed by atomic layer deposition (ALD).Type: ApplicationFiled: December 13, 2019Publication date: June 17, 2021Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Marc Currie, Virginia D. Wheeler, Guy Beadie
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Patent number: 11033706Abstract: In an example, a ventilator includes an outer container containing liquid, an inverted container submerged in the liquid to provide inverted container space between a closed top and an inner container liquid level; gas supply line to supply breathing gas to the inverted container space; and inhalation line having an inlet in the inverted container space to provide breathing gas to patient. The inverted container moves upward from a preset minimum elevation when the inverted container space reaches a hydrostatic delivery pressure and volume of the inverted container space increases. The inverted container stops moving upward and the gas supply line stops supplying when the inverted container reaches a preset maximum elevation. Based on a breath demand signal or preset timing, the inhalation line opens to permit flow of breathing gas to the patient at the hydrostatic delivery pressure, lowering the inverted container due to lost buoyancy resulting in sinkage.Type: GrantFiled: November 12, 2020Date of Patent: June 15, 2021Assignee: The Government of the United States of America, as represented by the Secretary of Homeland SecurityInventors: Bryson Jacobs, Savannah Lyle
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Patent number: 11035707Abstract: An optical flow meter includes a substrate; a microchannel with a fluid receiver; a fluid transmitter; a fluid member with an optical interaction region; a photo interaction region; an analytical light path, such that analytical light interacts with an analyte in a photo interaction region subsequent to an interaction of a pre-analyte with activation light in an optical interaction region to produce analyte; and a detection light path disposed in the substrate, arranged at an oblique angle or right angle to the fluid member proximate to the photo interaction region, and that: receives the photoanalyte light from the photo interaction region; and communicates the photoanalyte light from the microchannel to a photodetector, the optical flow meter determines a flow rate of the analyte.Type: GrantFiled: May 1, 2018Date of Patent: June 15, 2021Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCEInventors: Gregory Alan Cooksey, Paul Nathan Patrone, Anthony Jose Kearsley
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Patent number: 11035949Abstract: The present disclosure is directed to a measurement system for measuring a reflection coefficient of a test sample, including: a transceiver antenna configured to be coupled to a source of electromagnetic radiation; and a RAM positioned between the transceiver antenna and a measurement region of the transceiver antenna, wherein the RAM comprises an aperture substantially orthogonal to and substantially aligned with a transceiving axis of the transceiver antenna. A method for obtaining error correction of a measurement system and a method of measuring a reflection coefficient in a test sample are also provided.Type: GrantFiled: April 10, 2018Date of Patent: June 15, 2021Assignee: The Government of the United States of America, as represented by the Secretary of Homeland SecurityInventors: Peter Roland Smith, James Christopher Weatherall, Jeffrey Brian Barber, Barry Thomas Smith
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Patent number: 11035792Abstract: A nanohole array (NHA)-based plasmonic sensor (e.g., gas/condensed phase sensor), their preparation, and their use to detect and analyze samples, especially mixtures of chemicals/bio-chemicals.Type: GrantFiled: March 6, 2019Date of Patent: June 15, 2021Assignees: The George Washington University, GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGYInventors: Yangyang Zhao, Mona Zaghloul, Stephen Semancik, Kurt D. Benkstein
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Patent number: 11033917Abstract: Disclosed is a closable container of a mesh material having openings. When the container is closed, the openings are the only gaps in the container. The openings are no more than 150 microns in diameter.Type: GrantFiled: December 14, 2018Date of Patent: June 15, 2021Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventor: Scooter Johnson
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Patent number: 11035984Abstract: The invention relates to methods for fabricating antireflective surface structures (ARSS) on an optical element using a three-dimensional film layer applied to the surface of the optical element. The methods beneficially permit materials that do not exhibit local variation in physical and chemical properties to be provided with ARSS. Optical elements having ARSS on at least one surface are also provided.Type: GrantFiled: December 7, 2017Date of Patent: June 15, 2021Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Jesse A. Frantz, Lynda E. Busse, L. Brandon Shaw, Jasbinder S. Sanghera, Ishwar D. Aggarwal, Menelaos K. Poutous
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Publication number: 20210172889Abstract: An X-ray imaging system for reconstructing X-ray spectra includes an integrating detector and a measurement mask, including at least one physical filter, positioned between the integrating detector and an X-ray source spectrum. The integrating detector receives a masked X-ray spectrum after the source spectrum has been filtered in accordance with the measurement mask. As a result of the measurement mask containing one or more physical filters being combined, a measurement mask having energy band-pass regions can be generated, to cover the source spectrum. Measured data, based on the masked X-ray spectrum and characteristics of the measurement mask, is collected from the integrating detector. The X-ray imaging system reconstructs an X-ray spectrum and generates the reconstructed X-ray spectrum based on applying a predetermined algorithm, such as total variation minimization reconstruction, to the measured data.Type: ApplicationFiled: January 26, 2021Publication date: June 10, 2021Applicant: The Government of the United States of America, as represented by the Secretary of Homeland SecurityInventor: Robert E. Klueg
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Publication number: 20210171417Abstract: A nanoparticle of a decomposition product of a transition metal aluminum hydride compound, a transition metal borohydride compound, or a transition metal gallium hydride compound. A process of: reacting a transition metal salt with an aluminum hydride compound, a borohydride compound, or a gallium hydride compound to produce one or more of the nanoparticles. The reaction occurs in solution while being sonicated at a temperature at which the metal hydride compound decomposes. A process of: reacting a nanoparticle with a compound containing at least two hydroxyl groups to form a coating having multi-dentate metal-alkoxides.Type: ApplicationFiled: December 3, 2020Publication date: June 10, 2021Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Albert Epshteyn, Andrew P. Purdy
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Publication number: 20210171418Abstract: A nanoparticle of a decomposition product of a transition metal aluminum hydride compound, a transition metal borohydride compound, or a transition metal gallium hydride compound. A process of: reacting a transition metal salt with an aluminum hydride compound, a borohydride compound, or a gallium hydride compound to produce one or more of the nanoparticles. The reaction occurs in solution while being sonicated at a temperature at which the metal hydride compound decomposes. A process of: reacting a nanoparticle with a compound containing at least two hydroxyl groups to form a coating having multi-dentate metal-alkoxides.Type: ApplicationFiled: December 3, 2020Publication date: June 10, 2021Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Albert Epshteyn, Andrew P. Purdy
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Patent number: 11029428Abstract: Compositions including additive manufacturing materials incorporating radiological detection materials therein are provided. Also provided are apparatus and methods, which may be utilized to monitor and measure nuclear criticality events, and determine if personnel have been exposed to ionizing radiation. The compositions, apparatus, and methods beneficially improve accuracy in assessing radiation exposure, particularly neutron exposure, and reduce degradation of the radiological detection materials.Type: GrantFiled: May 6, 2019Date of Patent: June 8, 2021Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Luis A. Benevides, Alan L. Huston, Brian L. Justus, Barbara A. Marcheschi