Patents Assigned to Government of the United States
  • Patent number: 11939345
    Abstract: A physiologically stable fluorophore includes a terminal moiety including a terminal reactive site that reacts with a reactive group of a substrate; a stability linker covalently bonded to the terminal moiety; and a bridge moiety covalently bonded to the stability linker such that the stability linker is interposed through chemical bonds between the bridge moiety and the terminal moiety; and a fluorescent moiety covalently bonded to the bridge moiety of the redox moiety and including: an electron bandgap mediator that is covalently bonded to the bridge moiety; a coordinate center covalently bonded to the electron bandgap mediator and that forms a Zwitterionic member with an atom in the electron bandgap mediator; and a steric hinder bonded to the electron bandgap mediator to provide steric hindrance for protection of the coordinate center.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: March 26, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Jeremiah Wallace Woodcock, Jeffrey William Gilman, Douglas Matthew Fox
  • Patent number: 11940714
    Abstract: A quantum EIT-based optical switch includes a first waveguide, linear or nonlinear, a separate nonlinear waveguide evanescently coupled to the first waveguide, and a pump coupled to the nonlinear waveguide. A quantum STIRAP-based optical transduction device, which includes an auxiliary, intermediate spectral state for the quantum signal that aids efficient transduction of the quantum signal from the input spectral state to the output spectral state in a single device.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: March 26, 2024
    Assignees: University of Maryland, College Park, Government of the United States of America, as Represented by the Secretary of Commerce
    Inventors: Ivan A. Burenkov, Sergey V. Polyakov
  • Patent number: 11941100
    Abstract: An apparatus verifies hosted information associated with a user. The apparatus establishes, by the online host serving as a relying party system (RPS), a secure connection between the RPS and a user mobile-identification-credential device (UMD). The RPS sends a mobile identification credential (MIC) user information request to the UMD, via the secure connection, seeking release of MIC user information (official information). The RPS obtains from authorizing party system (APS) verification of the MIC user information received in response to the MIC user information request. The RPS stores the MIC user information as hosted information pertaining to the user. The RPS designates the hosted information as base truth information representing the user.
    Type: Grant
    Filed: May 4, 2023
    Date of Patent: March 26, 2024
    Assignee: The Government of the United States of America, represented by the Secretary of Homeland Security
    Inventors: Daniel A. Boyd, Kelli L Biegger, Chang Ellison, Brandon P. Gutierrez, Jason Lim, William Washington
  • Publication number: 20240098503
    Abstract: In an example, a provider system receives from a client device a request for client access. The provider system sends to the client device a request for identification information of the client. The provider system receives client information associated with a mobile identification credential (MIC) which the client device received from an authorizing party system (APS), the client having consented to release the client information to the provider system, and the client information having been verified by the APS. The provider system uses the verified client information associated with the MIC to verify or not verify the identity of the client. The provider system verifies the identity of the client before granting the client the request for client access.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 21, 2024
    Applicant: The Government of the United States of America, as represented by the Secretary of Homeland Security
    Inventors: Jason Lim, Daniel Boyd, Chang Ellison, William Washington
  • Publication number: 20240094425
    Abstract: A detector for detecting optically undetectable sub-cm orbital debris. A ring detector comprising a current pulse transformer (CPT) in which a conducting wire coil is wrapped around a loop of high permeability material having a magnetic nanoparticle (MNP) core. Debris objects in low earth orbit become charged as they pass through local plasma. As each charged debris object passes through the coil-wrapped loop, its current generates an induced voltage pulse, which can be used to detect the presence of the debris object. By fielding such a detector on a satellite, a long duration survey of the debris distribution in the LEO region can be made as the satellite's altitude is systematically varied.
    Type: Application
    Filed: March 3, 2023
    Publication date: March 21, 2024
    Applicant: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: William E. Amatucci, Gurudas I. Ganguli, Abhijit Sen, Christopher Crabtree
  • Publication number: 20240092767
    Abstract: Benzoxazine compounds, methods of making them, polymers made therefrom and methods of polymerizing the benzoxazines. These renewable benzoxazine monomers and polymers that utilize the variety of building blocks found in renewable plant biomass, demonstrate excellent processability and large temperature windows for processing of resin systems.
    Type: Application
    Filed: March 24, 2023
    Publication date: March 21, 2024
    Applicants: DREXEL UNIVERSITY, The Government of the United States of America, as represented by The Secretary of the Army
    Inventors: Giuseppe R. Palmese, Santosh K. Yadav, John J. LaScala
  • Patent number: 11933922
    Abstract: Hybrid subtractive-additive production of a superconducting multi-layer transition-edge sensor includes: forming a superconductor layer; forming a patterning photoresist on the superconductor layer; forming a sensor pattern in the patterning photoresist; subtractively forming, from the superconductor layer, the superconductor sensor layer; removing the patterning photoresist from the superconductor sensor layer; forming a template photoresist on the superconductor sensor layer; forming an inverse normal metal layer pattern in the template photoresist and exposing a bilayer portion of the superconductor sensor layer for addition of a normal metal layer; and additively forming the normal metal layer on the superconductor sensor layer such that the sensor pattern is interposed between the normal metal layer and the substrate.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: March 19, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Daniel Richard Schmidt, Joel Calvin Weber
  • Patent number: 11937361
    Abstract: A cathode emitter assembly includes a cathode tube having a gas feed portion and a plasma outflow portion; an outer annular cathode insert in the plasma outflow portion of the cathode tube; an inner cathode insert in the plasma outflow section of the cathode tube; and an annular plasma emission portion defined between an inner surface of the outer annular cathode insert and an outer surface of the inner cathode insert.
    Type: Grant
    Filed: February 9, 2022
    Date of Patent: March 19, 2024
    Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Michael McDonald, Marcel Georgin
  • Publication number: 20240085585
    Abstract: Examples are directed toward systems and methods relating to security screening. For example, a screening system includes a sensor array to sense a gravitational field caused by an item, and a conveyor to convey the item through sensing positions for scanning by the sensor array. A controller acquires weight measurement information from sensor elements, and gravitational measurement information from the sensor array. The conveyor incrementally advances the item through additional sensing positions to acquire weight measurement information and gravitational measurement information. The controller performs tomographic reconstruction to generate a tomographic image of the item, using a generated weight map as a static weight input vector and using a generated mass map as a static mass input vector for the tomographic reconstruction.
    Type: Application
    Filed: November 24, 2023
    Publication date: March 14, 2024
    Applicant: The Government of the United States of America, as represented by the Secretary of Homeland Security
    Inventor: James Henry Remer
  • Publication number: 20240083754
    Abstract: Disclosed is a method of irradiating a composition having water and hydrogen-terminated nanodiamonds with light that generates water-solvated electrons from the nanodiamonds. The method can be used to degrade fluoroalkyl compounds such as perfluorooctane sulfonate.
    Type: Application
    Filed: November 21, 2023
    Publication date: March 14, 2024
    Applicant: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Bradford B. Pate, William Maza, Vanessa Breslin, Paul A. DeSario, Tatyana I. Feygelson, Albert Epshteyn, Jeffrey C. Owrutsky, Carlos Hangarter
  • Publication number: 20240082233
    Abstract: Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I): A compound of Formula (I) can be administered prior to potential exposure of a species of Plasmodium, during potential exposure of a species of Plasmodium, and after potential exposure of a species of Plasmodium. The methods of the invention also pertains to kits comprising specific doses of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I), and instructions for administration of dosing quantity and frequency. The methods of the invention also pertain to determining doses of Formula (I) that meet the general regulatory requirement for a drug to be efficacious in the prevention of malaria in malaria-naïve subjects.
    Type: Application
    Filed: August 30, 2023
    Publication date: March 14, 2024
    Applicants: 60 DEGREES PHARMACEUTICALS LLC, THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY
    Inventors: Geoffrey S. DOW, Bryan L. SMITH, John P. JONES, Moshe SHMUKLARSKY, Budda BALASUBRAHMANYAM
  • Publication number: 20240085434
    Abstract: A method of predicting acute mountain sickness (AMS). The method includes collecting a urine sample from a subject and analyzing the urine sample for a quantity of at least one metabolite selected from the group consisting of creatine, taurine, N-methylhistidine, hypoxanthine, 1-methylnicotinamide, 4-hydroxyphenylpyruvate, acetylcarnitine, and 3-methylhistidine. The quantity is compared to a threshold value for the respective metabolite. Based on the comparison, it is determined whether the subject is susceptible to experience AMS at high altitudes.
    Type: Application
    Filed: September 11, 2023
    Publication date: March 14, 2024
    Applicant: Government of the United States as Represented by the Secretary of the Air Force
    Inventors: Camilla A. Mauzy, James P. Karl
  • Publication number: 20240084034
    Abstract: The present disclosure is directed to antibodies binding to Glypican 2 and methods of using such antibodies to treat cancers that express or overexpress the Glypican 2 antigen.
    Type: Application
    Filed: October 31, 2023
    Publication date: March 14, 2024
    Applicants: THE CHILDREN'S HOSPITAL OF PHILADELPHIA, THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY
    Inventors: John M. MARIS, Kristopher R. BOSSE, Dimiter DIMITROV, Zhongyu ZHU, Dontcho V. JELEV
  • Publication number: 20240074786
    Abstract: A kit for disposing one or more functional additives into an anatomical cavity of a patient, and particularly into the nasopharyngeal region of a patient. The functional additives may be designed to assist the patient, the doctor or both during a surgical procedure. The kit has an apparatus with a hollow deployment tube into which the functional additive may be removably disposed upon manipulation by a doctor. The kit may comprise a plurality of mutually identical or mutually different functional additives and optionally be used with surgical tampons.
    Type: Application
    Filed: September 28, 2022
    Publication date: March 7, 2024
    Applicant: The Government of the United States, as represented by the Director of the Defense Health Agency
    Inventors: Andrew Boston, Mostafa Ahmed
  • Publication number: 20240078795
    Abstract: Systems and methods of detecting a vortex made by a travelling object is disclosed. In some configurations, a graphic recognition algorithm and vortex similarity engine are used to determine whether a visual media file captured by a media collector contains a vortex. The vortex similarity engine may be configured to determine or identify certain properties about the travelling object based on the travelling object vortex. In some configurations, a computer may trigger an alert if a travelling object vortex is not expected to be in the visual media file.
    Type: Application
    Filed: November 2, 2023
    Publication date: March 7, 2024
    Applicant: The Government of the United States of America, as represented by the Secretary of Homeland Security
    Inventor: Mark Fry
  • Publication number: 20240075261
    Abstract: An apparatus that includes a conformable and compressible nasopharyngeal tampon and a method for delivering the tampon to an anatomical cavity of a patient. The tampon is configured to collect and remove posterior nasal fluid from a patient. The tampon may be compressably and slidably disposed in a longitudinally extending deployment tube having mutually opposed proximal and distal ends. A longitudinal plunger is slidably disposed within and extends out of the proximal end of the deployment tube. The distal end of the plunger is disposed in choanae and/or nasopharynx of the patient. Upon manual actuation, the plunger is activated to deliver the tampon to the nasopharyngeal region of a mammalian patient. Optionally, positioning strings may be joined to the tampon, to fine tune positioning of the tampon within the choanae and/or nasopharynx.
    Type: Application
    Filed: September 28, 2022
    Publication date: March 7, 2024
    Applicant: the Government of the United States as represented by the Secretary of the Air Force
    Inventors: Mostafa Ahmed, Andrew Boston
  • Patent number: 11922299
    Abstract: A computer processor includes an on-chip network and a plurality of tiles. Each tile includes an input circuit to receive a voltage signal from the network, and a crossbar array, including at least one neuron. The neuron includes first and second bit lines, a programmable resistor connecting the voltage signal to the first bit line, and a comparator to receive inputs from the two bit lines and to output a voltage, when a bypass condition is not active. Each tile includes a programming circuit to set a resistance value of the resistor, a pass-through circuit to provide the voltage signal to an input circuit of a first additional tile, when a pass-through condition is active, a bypass circuit to provide values of the bit lines to a second additional tile, when the bypass condition is active; and at least one output circuit to provide an output signal to the network.
    Type: Grant
    Filed: April 3, 2023
    Date of Patent: March 5, 2024
    Assignee: The Government of the United States as represented by the Director, National Security Agency
    Inventor: David J. Mountain
  • Patent number: 11922676
    Abstract: Systems and methods of detecting a vortex made by a travelling object is disclosed. Techniques include positioning a media collector to capture a visual media file of the vortex. In some configurations, a graphic recognition algorithm and vortex similarity engine are used to determine whether a visual media file captured by a media collector contains a vortex. In some configurations, a computer may trigger an alert if a travelling object vortex is not expected to be in the visual media file.
    Type: Grant
    Filed: November 15, 2022
    Date of Patent: March 5, 2024
    Assignee: The Government of the United States of America, as represented by the Secretary of Homeland Security
    Inventor: Mark A. Fry
  • Patent number: 11920035
    Abstract: This disclosure concerns electrically conducting poly(pyrazoles). The concept of oligomerizing and polymerizing substituted aminopyrazole derivatives combined with a monomer activation procedure involving base-mediated conversion of the protonated pyrazole ring nitrogen to amine salt was developed. This disclosure concerns the specific chemistries needed for the synthesis of a pyrazole monomer used in the polymer synthesis. The procedure used for blending the novel polypyrazoles with other compounds needed for construction of solar cells for testing was developed. This disclosure concerns the concept of using these types of heteroatom-rich, electron-deficient oligomers or polymers as n-dopable or p-dopable electron acceptors in photovoltaic cells. This disclosure concerns synthesizing the starting monomer compounds and polypyrazoles.
    Type: Grant
    Filed: October 25, 2022
    Date of Patent: March 5, 2024
    Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Brett D. Martin, Ian D. Giles, Jawad Naciri, Paul T. Charles, Scott A. Trammell, Jeffrey R. Deschamps, Jeffrey C. Depriest
  • Patent number: 11924349
    Abstract: Systems and methods for secure distribution of biometric matching processing are provided. Certain configurations include homomorphic encrypting of captured biometric information. In some configurations, the biometric information is classified without decryption between a first identity class and a second identity class. The biometric information may be formed as a feature vector. A homomorphic encrypted feature vector may be formed by homomorphic encrypting of the biometric information.
    Type: Grant
    Filed: December 13, 2022
    Date of Patent: March 5, 2024
    Assignee: The Government of the United States of America, as represented by the Secretary of Homeland Security
    Inventor: Arun Vemury