Patents Assigned to Graffinity Pharmaceuticals AG
  • Patent number: 7955638
    Abstract: The present invention relates to binding surfaces for the immobilization of ligands, ligand surfaces and structured surface arrays which present a plurality of identical or different ligands. The invention further relates to a process for the production and the use of such surfaces and to specific binder molecules which can be used for the preparation thereof.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: June 7, 2011
    Assignee: Graffinity Pharmaceuticals AG
    Inventors: Stefan Dickopf, Holger Ottleben, Harald Rau, Renate Sekul, Kristina Schmidt, Dirk Vetter
  • Patent number: 7842242
    Abstract: A device for optically coupling a first optical element to a second optical element comprises a first optical element with a first radiation penetration surface; a second optical element with a second radiation penetration surface located across from the first radiation penetration surface; and a chamber delimited by the first and second radiation penetration surfaces and a circumferentially closed side wall which connects the first and second radiation penetration surfaces. The circumferentially closed side wall defines a first sector in the first radiation penetration surface and a second sector in the second radiation penetration surface, the area of the first sector being smaller than the area of the first radiation penetration surface, and the area of the second sector being smaller than the area of the second radiation penetration surface.
    Type: Grant
    Filed: April 1, 2004
    Date of Patent: November 30, 2010
    Assignee: Graffinity Pharmaceuticals AG
    Inventors: Stefan Dickopf, Thomas Perschke, Mladen Nedic, Kristina Schmidt
  • Publication number: 20080027035
    Abstract: The invention relates to compounds of formula (I) wherein Z, R1-5, X, n, A1 and A2 have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.
    Type: Application
    Filed: December 9, 2004
    Publication date: January 31, 2008
    Applicant: GRAFFINITY PHARMACEUTICALS AG
    Inventors: Paul John Edwards, Meritxell Lopez-Canet, Achim Feurer, Silvia Cerezo-Galvez, Victor Ghalio Matassa, Sonia Nordhoff, Meinolf Thiemann, Oliver Hill
  • Publication number: 20070273883
    Abstract: The invention relates to a sensor arrangement comprising a radiation-conducting substrate, said arrangement having a plurality of sensor fields and separating regions for separating the individual sensor fields from the respectively adjacent sensor fields. Said separating regions are formed by a separating agent layer that causes a reflectivity lower than 0.5 for radiation from the substrate on the interface between the separating agent layer and the substrate, at least in a first region adjacent to the interface between the separating agent layer and the substrate, and an extinction higher than 0.95 at least in a second region located above the first region, on the side opposing the substrate.
    Type: Application
    Filed: June 21, 2004
    Publication date: November 29, 2007
    Applicant: Graffinity Pharmaceuticals AG
    Inventors: Stefan Dickopf, Klaus Burkert, Alexander Maier, Kristina Schmidt
  • Publication number: 20070248300
    Abstract: A device for optically coupling a first optical element to a second optical element comprises a first optical element with a first radiation penetration surface; a second optical element with a second radiation penetration surface located across from the first radiation penetration surface; and a chamber delimited by the first and second radiation penetration surfaces and a circumferentially closed side wall which connects the first and second radiation penetration surfaces. The circumferentially closed side wall defines a first sector in the first radiation penetration surface and a second sector in the second radiation penetration surface, the area of the first sector being smaller than the area of the first radiation penetration surface, and the area of the second sector being smaller than the area of the second radiation penetration surface.
    Type: Application
    Filed: April 1, 2004
    Publication date: October 25, 2007
    Applicant: Graffinity Pharmaceuticals AG
    Inventors: Stefan Dickopf, Thomas Perschke, Mladen Nedic, Kristina Schmidt
  • Patent number: 6695369
    Abstract: The invention relates to a device and a method for picking up individual objects or particles and placing them in containers or cavities filled with liquid. The invention allows in particular a simple handling of the objects and thus considerably reduces the operation costs of such a plant (FIG. 2). In this method and device, an adhesive is applied to an end portion of a transport structure. An object to be transported is held by the adhesive until it is delivered to the desired location.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: February 24, 2004
    Assignee: Graffinity Pharmaceuticals AG
    Inventors: Kristina Schmidt, Dirk Vetter