Patents Assigned to Grandhope Biotech Co. Ltd.
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Patent number: 8366770Abstract: A biological nerve guide for implantation into a human body is made by providing a natural animal tissue membrane, crosslinking and fixing the membrane, minimizing the antigens from the membrane, tanning the membrane, coupling an active layer to an inner surface of the membrane, cutting the membrane into a desired shape and size, positioning the cut membrane onto a rod-shaped mold so that the cut membrane assumes a cylindrical configuration, and attaching a spiral support to the outer surface of the cut membrane.Type: GrantFiled: November 10, 2009Date of Patent: February 5, 2013Assignee: Grandhope Biotech Co. Ltd.Inventor: Guo-Feng Xu
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Patent number: 8292799Abstract: A prosthetic device for implantation into a human body is made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate to improve its mechanical properties, and coupling an anticoagulant to an inner surface of the substrate to form an anticoagulant surface layer.Type: GrantFiled: July 28, 2006Date of Patent: October 23, 2012Assignee: Grandhope Biotech Co., Ltd.Inventor: Guo-Feng Xu
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Patent number: 8197500Abstract: An aneurysm clip has a biological membrane and a metal clip. The membrane is harvested from an animal, crosslinked, and then has its antigens minimized. The membrane also has an active layer coupled thereto. The metal clip has a first clip bar and a second clip bar that are attached to each in a biased manner, a first clip arm that extends perpendicularly from the second clip bar, and a second clip arm that extends perpendicularly from the first clip bar. A first end of the biological membrane is coupled to the first clip arm, and a second end of the biological membrane is coupled to the second clip arm in a manner that defines a receiving portion.Type: GrantFiled: August 1, 2006Date of Patent: June 12, 2012Assignee: Grandhope Biotech Co., Ltd.Inventors: Song-Tao Qi, Guo-Feng Xu
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Publication number: 20120135924Abstract: A cartilage prosthesis is made according to a method that includes the steps of collecting animal material from a bovine, ovine or porcine source, the animal material being a cartilage, shaping the animal material to provide a desired shape for the cartilage implant, removing cells from the animal material, crosslinking the animal material, removing antigens from the animal material, subjecting the animal material to an alkaline treatment, coupling into the animal material active substances which are capable of adhering growth factor and stem cell, and packing the animal material in a container that contains a sterilization solution.Type: ApplicationFiled: January 31, 2012Publication date: May 31, 2012Applicant: GRANDHOPE BIOTECH CO., LTD.Inventors: Guo-Feng Xu, Bin Xu
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Publication number: 20120128785Abstract: A nasal bridge implant is made according to a method that includes the steps of collecting animal material from a bovine or porcine source, the animal material being either a tendon or a ligament, removing cells from the animal material, shaping the animal material to provide a desired shape for the nasal bridge implant, crosslinking the animal material, removing antigens from the animal material, subjecting the animal material to an alkaline treatment, coupling into the animal material active substances which are capable of adhering growth factor and stem cell, and packing the animal material in a container that contains a sterilization solution.Type: ApplicationFiled: January 30, 2012Publication date: May 24, 2012Applicant: GRANDHOPE BIOTECH CO., LTD.Inventors: Guo-Feng Xu, Bin Xu
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Publication number: 20120123549Abstract: A biological jawbone prosthesis is made according to a method that includes the steps of collecting animal material from a bovine or porcine source, the animal material being a jawbone, shaping the animal material to provide a desired shape for the jawbone implant, removing cells from the animal material, crosslinking the animal material, removing antigens from the animal material, subjecting the animal material to an alkaline treatment, coupling into the animal material active substances which are capable of adhering growth factor and stem cell, and packing the animal material in a container that contains a sterilization solution.Type: ApplicationFiled: January 27, 2012Publication date: May 17, 2012Applicant: GRANDHOPE BIOTECH CO., LTD.Inventors: Guo-Feng Xu, Bin Xu
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Patent number: 8100970Abstract: A biological surgical patch made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate, and incorporating an active layer in the substrate.Type: GrantFiled: December 15, 2006Date of Patent: January 24, 2012Assignee: Grandhope Biotech Co., Ltd.Inventor: Guo-Feng Xu
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Patent number: 7824447Abstract: A prosthesis for implantation into a human body is made by a method that includes the steps of providing a natural animal ligament or tendon that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate to improve its mechanical properties, and coupling an active layer to the substrate.Type: GrantFiled: February 3, 2010Date of Patent: November 2, 2010Assignee: Grandhope Biotech Co. Ltd.Inventor: Guo-Feng Xu
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Patent number: 7820871Abstract: A biological wound dressing is made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, and incorporating an active layer in the substrate.Type: GrantFiled: December 15, 2006Date of Patent: October 26, 2010Assignee: Grandhope Biotech Co., Ltd.Inventor: Guo-Feng Xu
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Patent number: 7674289Abstract: A prosthesis for implantation into a human body is made by a method that includes the steps of providing a natural animal ligament or tendon that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate to improve its mechanical properties, and coupling an active layer to the substrate.Type: GrantFiled: July 28, 2006Date of Patent: March 9, 2010Assignee: Grandhope Biotech Co., Ltd.Inventor: Guo-Feng Xu
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Patent number: 7618653Abstract: A biological nerve guide for implantation into a human body is made by providing a natural animal tissue membrane, crosslinking and fixing the membrane, minimizing the antigens from the membrane, tanning the membrane, coupling an active layer to an inner surface of the membrane, cutting the membrane into a desired shape and size, positioning the cut membrane onto a rod-shaped mold so that the cut membrane assumes a cylindrical configuration, and attaching a spiral support to the outer surface of the cut membrane.Type: GrantFiled: December 18, 2006Date of Patent: November 17, 2009Assignee: Grandhope Biotech Co. Ltd.Inventor: Guo-Feng Xu