Abstract: The present invention relates to a process for the preparation of amino alcohol derivatives or salts thereof which may be used as intermediates in the preparation of HIV reverse transcriptase inhibitors, more preferably Carbovir and Abacavir. The present invention more specifically relates to a process for the preparation of (1S, 4R)-4-amino-2-cyclopentene-1-methanol of Formula IIIa.
Abstract: The present invention relates to an improved and industrially advantageous process for the preparation of Rifaximin with high purity and yield. Particularly, the present invention relates to improved processes for the preparation of Rifaximin from Rifamycin O and S. More particularly the present invention relates to a process for the preparation of Rifaximin through 3-halorifamycin S. The present invention further relates to a novel polymorph of Rifaximin and process for its preparation.
Abstract: The present invention relates to continuous processes for the preparation of primary and secondary N-acetylated aromatic amines of formula I or O-acetylated product of o-hydroxy benzoic acid of Formula II using acetic acid as an acetylating agent. wherein R1 has a definition of hydrogen atom, C1-C4 alkyl group or C1-C4 alkoxy group.
Type:
Grant
Filed:
July 29, 2011
Date of Patent:
August 11, 2015
Assignee:
GRANULES INDIA LIMITED
Inventors:
Arumugam Bhaskar Krishna, Abul Hasnat, Sirisha Pamidipati
Abstract: The present invention relates to continuous processes for the preparation of primary and secondary N-acetylated aromatic amines of formula I or O-acetylated product of o-hydroxy benzoic acid of Formula II using acetic acid as an acetylating agent. wherein R1 has a definition of hydrogen atom, C1-C4 alkyl group or C1-C4 alkoxy group.