Patents Assigned to Grape King Inc.
  • Method for producing novel ?-lactam antibiotic from protoplast fusion strain
    Patent number: 7241588
    Abstract: The present invention provides a method for producing a novel ?-lactam antibiotic from a protoplast fusion strain. The method is to fermentatively culture the protoplast fusion strain of Penicillium chrysogenum and Cephalosporium acremonium. The ferment filtrate is isolated, lyophilized, and extracted by acetone or acetone/methanol. The extract is concentrated by decompression, and then analyzed by preparation type HPLC to isolate the active antibiotic compound.
    Type: Grant
    Filed: September 9, 2003
    Date of Patent: July 10, 2007
    Assignee: Grape King Inc.
    Inventors: Chin-Chu Chen, Ying-Shih Feng, Charng-Cherng Chyau, Ching-Nung Chen, Shih-Jeng Huang, Yen-Lien Chen, Hung-Ping Tseng, Wei-Hui Chung, Yi-Hsuan Chen