Patents Assigned to Graphium Biosciences, Inc.
  • CONTINUOUS ENZYMATIC PERFUSION REACTOR SYSTEM
    Publication number: 20240058755
    Abstract: The present disclosure relates to methods, systems, and apparatus for efficient continuous production of hydrophobic products with the simultaneous retention of substrates.
    Type: Application
    Filed: December 13, 2021
    Publication date: February 22, 2024
    Applicant: Graphium Biosciences, Inc.
    Inventors: Tyrel R. DEUTSCHER, Brandon J. ZIPP, Janee' M. HARDMAN
  • CANNABINOID GLYCOSIDE PRODRUGS AND METHODS OF SYNTHESIS
    Publication number: 20230346952
    Abstract: The present invention provides tetrahydrocannabinol glycoside and cannabidiol glycoside prodrugs and pharmaceutical compositions comprising these compounds, and their use for the site-specific delivery of tetrahydrocannabinol or cannabidiol. Also provided are processes for the preparation of purified tetrahydrocannabinol glycoside and cannabidiol glycoside prodrugs.
    Type: Application
    Filed: March 13, 2023
    Publication date: November 2, 2023
    Applicant: Graphium Biosciences, Inc.
    Inventors: Brandon J. ZIPP, Janee’ M. HARDMAN, Robert T. BROOKE, Tyrel R. DEUTSCHER
  • CANNABINOID GLYCOSIDES AND USES THEREOF
    Publication number: 20220227726
    Abstract: The present invention provides tetrahydrocannabinol glycoside and cannabidiol glycoside prodrugs and pharmaceutical compositions comprising these compounds, and their use for the site specific delivery of tetrahydrocannabinol or cannabidiol. Also provided are processes for the preparation of purified tetrahydrocannabinol glycoside and cannabidiol glycoside prodrugs.
    Type: Application
    Filed: October 26, 2021
    Publication date: July 21, 2022
    Applicant: Graphium Biosciences, Inc.
    Inventors: Janee' M. HARDMAN, Brandon J. ZIPP, Tyrel R. DEUTSCHER
  • CANNABINOID GLYCOSIDE PRODRUGS AND METHODS OF SYNTHESIS
    Publication number: 20220168428
    Abstract: The present invention relates to cannabinoid glycoside prodrugs suitable for site- and tissue-specific delivery of cannabinoid molecules. The present invention also relates to methods of forming the cannabinoid glycoside prodrugs through glycosyltransferase mediated glycosylation of cannabinoid molecules.
    Type: Application
    Filed: November 16, 2021
    Publication date: June 2, 2022
    Applicant: Graphium Biosciences, Inc.
    Inventors: Brandon J. Zipp, Janee M. Hardman, Robert T. Brooke
  • ANTIMICROBIAL COMPOSITIONS COMPRISING CANNABINOIDS AND METHODS OF USING THE SAME
    Publication number: 20220071950
    Abstract: The invention relates is directed to antimicrobial compositions comprising cannabinoid compounds and methods of utilizing the antimicrobial compositions to inhibit the growth of microorganisms, to treat and/or prevent microbial infections.
    Type: Application
    Filed: November 18, 2021
    Publication date: March 10, 2022
    Applicant: Graphium Biosciences, Inc.
    Inventors: Brandon Joel Zipp, Robert Thomas Brooke
  • Cannabinoid glycoside prodrugs and methods of synthesis
    Patent number: 11207414
    Abstract: The present invention relates to cannabinoid glycoside prodrugs suitable for site- and tissue-specific delivery of cannabinoid molecules. The present invention also relates to methods of forming the cannabinoid glycoside prodrugs through glycosyltransferase mediated glycosylation of cannabinoid molecules.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: December 28, 2021
    Assignee: Graphium Biosciences, Inc.
    Inventors: Brandon J. Zipp, Janee M. Hardman, Robert T. Brooke
  • Antimicrobial compositions comprising cannabinoids and methods of using the same
    Patent number: 11207291
    Abstract: The invention relates is directed to antimicrobial compositions comprising cannabinoid compounds and methods of utilizing the antimicrobial compositions to inhibit the growth of microorganisms, to treat and/or prevent microbial infections.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: December 28, 2021
    Assignee: Graphium Biosciences, Inc.
    Inventors: Brandon Joel Zipp, Robert Thomas Brooke