Patents Assigned to Great Lakes Neurotechnologies Inc
  • Patent number: 9974478
    Abstract: The present invention relates to systems and methods for helping subjects improve safety and efficiency of their movements; particularly subjects who have suffered an injury or suffer from a movement or other such disorder. More particularly, the present invention relates to such a system and method for monitoring a subject's movement to detect or predict unsafe, undesirable, or impaired movements, or symptoms of movement disorders, and also a system for providing possible treatment methods for such conditions. The present invention further relates to a method and system of providing cues or stimuli to the subject when such unsafe or undesirable movements, instabilities or symptoms are detected or predicted. Most particularly, the present invention relates to a subject-customized and adaptive movement recovery system, and method of providing therapy and training to improve functional motor recovery and safety of movement of a subject suffering from an injury or from movement disorder(s).
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: May 22, 2018
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Elizabeth Brokaw, Dustin A. Heldman, Christopher L. Pulliam, Joseph P. Giuffrida
  • Patent number: 9877679
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: January 30, 2018
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventor: Joseph Giuffrida
  • Patent number: 9877680
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a treatment delivery system for treating a subject in response to changes in the severity of a subject's symptoms. The present invention further provides for a system and method, which can accurately quantify symptoms of movement disorders, utilizing continuously obtained kinetic information to be analyzed, accurately distinguishing between symptoms of movement disorders and activities of daily living, relating quantified symptoms to a standard clinical rating scale, and correlating a subject's symptoms with certain physiological and environmental factors. The present invention still further provides for home monitoring of symptoms in subjects with these movement disorders in order to capture the complex fluctuation patterns of the disease over the course of days, weeks, months, or years.
    Type: Grant
    Filed: February 15, 2016
    Date of Patent: January 30, 2018
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P Giuffrida, Dustin A Heldman, Thomas O Mera
  • Patent number: 9861283
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: January 9, 2018
    Assignee: Great Lakes NeuroTechnologies Inc
    Inventor: Joseph Giuffrida
  • Patent number: 9782122
    Abstract: The present invention relates to systems, devices and methods for acquiring, measuring, monitoring, processing and analyzing physiological signals. More particularly, the present invention relates to using physiological signals to determine a subject's response to various conditions, variables or constraints. Still more particularly, the present invention relates to monitoring the subject's external body motion and/or environmental factors and determining the amount of pain a subject is suffering as a result of the motion and factors. Still more particularly, the present invention relates to a system, device and methods of quantifying a subject's pain to provide an objective measurement of the subject's pain. The present invention further relates to establishing and improving pain management protocols and therapy or treatment for the subject's pain based on the quantified pain measurement.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: October 10, 2017
    Assignee: Great Lakes NeuroTechnologies Inc
    Inventors: Christopher L Pulliam, Joseph P Giuffrida
  • Patent number: 9717920
    Abstract: The present invention relates to methods for tuning treatment parameters in movement disorder therapy systems. The present invention further relates to a system for screening patients to determine viability as candidates for certain therapy modalities, such as deep brain stimulation (DBS). The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of tuning a therapy device using objective quantified movement disorder symptom data acquired by a movement disorder diagnostic device to determine the therapy setting or parameters to be provided to the subject via his or her therapy device.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: August 1, 2017
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A Heldman, Christopher L Pulliam, Joseph P Giuffrida, Thomas O Mera
  • Patent number: 9696228
    Abstract: The present invention is related to a sensor for simultaneously measuring both normal and shear forces applied to the sensor, and further a statically responsive sensor for measuring shear forces. The present invention further includes a method of designing an object or a device using these sensors.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: July 4, 2017
    Assignee: Great Lakes Neurotechnologies Inc.
    Inventor: Matthew D. Tarler
  • Patent number: 9662502
    Abstract: A system and method for tuning the parameters of a therapeutic medical device comprises a movement measurement data acquisition system capable of wireless transmission; processing comprising kinematic feature extraction, a scoring algorithm trained using scores from expert clinicians, a therapeutic device parameter setting adjustment suggestion algorithm preferably trained using the parameter setting adjustment judgments of expert clinicians; and a display and/or means of updating the parameter settings of the treatment device. The invention facilitates the treatment of movement disorders including Parkinson's disease, essential tremor and the like by optimizing deep brain stimulation (DBS) parameter settings, eliminating as much as possible motor symptoms and reducing time and costs of surgical and outpatient procedures and improving patient outcomes.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: May 30, 2017
    Assignee: Great Lakes Neurotechnologies Inc.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman, Thomas O. Mera
  • Patent number: 9314190
    Abstract: Most particularly, the present invention relates to a customized and adaptive movement recovery system and a method of improving the functional motor recovery of a subject with a movement disorder. The present invention provides for a system and method, which in some embodiments can accurately quantify treatment device parameters and protocols including electrical stimulation amplitude (volts/amps), frequency (Hz), and pulse width (microseconds), and medication titrations, doses, and times by utilizing accelerometric, gyroscopic or other movement related information, such as electromyography (EMG) data, or the like, and a central database, or system of databases, of patient and treatment histories. In other embodiments, the system and method provide for an adaptive central database system and automated control of movement disorder treatment devices.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: April 19, 2016
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P Giuffrida, Dustin A Heldman, Thomas O Mera
  • Patent number: 9302046
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a treatment delivery system for treating a subject in response to changes in the severity of a subject's symptoms. The present invention further provides for a system and method, which can accurately quantify symptoms of movement disorders, utilizing continuously obtained kinetic information to be analyzed, accurately distinguishing between symptoms of movement disorders and activities of daily living, relating quantified symptoms to a standard clinical rating scale, and correlating a subject's symptoms with certain physiological and environmental factors. The present invention still further provides for home monitoring of symptoms in subjects with these movement disorders in order to capture the complex fluctuation patterns of the disease over the course of days, weeks, months, or years.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: April 5, 2016
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P Giuffrida, Dustin A Heldman, Thomas O Mera
  • Patent number: 9282928
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: March 15, 2016
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventor: Joseph Giffrida
  • Patent number: 9238142
    Abstract: The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: January 19, 2016
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A Heldman, Christopher L Pulliam, Joseph P Giuffrida, Thomas O Mera
  • Patent number: 9227056
    Abstract: The present invention relates to a system and methods for noninvasively providing therapy for movement disorder symptoms. The present invention provides such a therapy system which provides trans-cranial direct current stimulation (tDCS) in order to treat those symptoms and the disorders. The present invention further provides such tDCS therapy while the subject sleeps in order to minimize the time required and impact of the therapy on the subject's waking life. The system, methods, and devices of the present invention are intended to provide a low-dose electrical current, trans-cranially, to a specific area of the subject's brain while he or she sleeps in order to decrease the occurrence, severity, and duration of the symptoms of movement disorders. The present invention aims to reduce the amount of medication necessary, counteract the effects of medication wearing off during sleep, and to overall improve the quality of life of subjects suffering from movement disorders.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: January 5, 2016
    Assignee: Great Lakes NeuroTechnologies, Inc.
    Inventors: Dustin A Heldman, Joseph P Giuffrida
  • Patent number: 9211417
    Abstract: The present invention relates to methods for tuning treatment parameters in movement disorder therapy systems. The present invention further relates to a system for screening patients to determine viability as candidates for certain therapy modalities, such as deep brain stimulation (DBS). The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of tuning a therapy device using objective quantified movement disorder symptom data acquired by a movement disorder diagnostic device to determine the therapy setting or parameters to be provided to the subject via his or her therapy device.
    Type: Grant
    Filed: June 15, 2013
    Date of Patent: December 15, 2015
    Assignee: Great Lakes NeuroTechnologies Inc
    Inventors: Dustin A Heldman, Christopher L Pulliam, Joseph P Giuffrida, Thomas O Mera
  • Patent number: 9149229
    Abstract: The present invention is related, in general, to a wireless electrode patch and/or a wireless system for measuring the physiological condition of a subject, more particularly to an electrode patch for ECG monitoring, and a method of sensing, analyzing and/or transmitting or relaying a physiological signal. The wireless system and/or wireless electrode patch of the present invention is preferably lightweight and compact. The wireless electrode patch preferably additionally provides a low-power system for extended battery life and use. The wireless electrode patch and/or wireless system still further preferably allows for good and reliable measurement of physiological signals from the subject. The wireless electrode patch is still preferably simple enough to apply as a single patch, but versatile enough to be reconfigured as more than one patch.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: October 6, 2015
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventor: Matthew David Tarler
  • Patent number: 8845557
    Abstract: The present invention relates to a movement disorder monitor with high sensitivity, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately and repeatably quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and/or electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides substantially real-time remote access to data by the clinician or physician.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: September 30, 2014
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman
  • Patent number: 8843201
    Abstract: The present invention relates to a system and methods for noninvasively providing therapy for movement disorder symptoms. The present invention provides such a therapy system which provides trans-cranial direct current stimulation (tDCS) in order to treat those symptoms and the disorders. The present invention further provides such tDCS therapy while the subject sleeps in order to minimize the time required and impact of the therapy on the subject's waking life. The system, methods, and devices of the present invention are intended to provide a low-dose electrical current, trans-cranially, to a specific area of the subject's brain while he or she sleeps in order to decrease the occurrence, severity, and duration of the symptoms of movement disorders. The present invention aims to reduce the amount of medication necessary, counteract the effects of medication wearing off during sleep, and to overall improve the quality of life of subjects suffering from movement disorders.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: September 23, 2014
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A Heldman, Joseph P Giuffrida
  • Publication number: 20140257141
    Abstract: The present invention relates to a movement disorder monitor with high sensitivity, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately and repeatably quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and/or electromyography (EMU) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides substantially real-time remote access to data by the clinician or physician.
    Type: Application
    Filed: March 5, 2013
    Publication date: September 11, 2014
    Applicant: GREAT LAKES NEUROTECHNOLOGIES INC.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman
  • Patent number: 8679038
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: March 25, 2014
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventor: Joseph Giuffrida
  • Publication number: 20130123684
    Abstract: A system and method for tuning the parameters of a therapeutic medical device comprises a movement measurement data acquisition system capable of wireless transmission; processing comprising kinematic feature extraction, a scoring algorithm trained using scores from expert clinicians, a therapeutic device parameter setting adjustment suggestion algorithm preferably trained using the parameter setting adjustment judgments of expert clinicians; and a display and/or means of updating the parameter settings of the treatment device. The invention facilitates the treatment of movement disorders including Parkinson's disease, essential tremor and the like by optimizing deep brain stimulation (DBS) parameter settings, eliminating as much as possible motor symptoms and reducing time and costs of surgical and outpatient procedures and improving patient outcomes.
    Type: Application
    Filed: June 3, 2011
    Publication date: May 16, 2013
    Applicant: GREAT LAKES NEUROTECHNOLOGIES INC.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman, Thomas O. Mera