Abstract: The invention relates to an ophthalmoscope comprising a camera and an associated illumination device; the invention further concerns a novel method for processing a plurality of images of the eye taken by said device; and software, typically included in said ophthalmoscope, for executing said method.

Abstract: The invention relates to an ophthalmoscope comprising a camera and an associated illumination device; the invention further concerns a novel method for processing a plurality of images of the eye taken by said device; and software, typically included in said ophthalmoscope, for executing said method.

Abstract: The present invention provides a novel lactate difference imaging (LDI) technique, allowing assessment of the metabolic responses of tissue over a period of time. This approach utilizes lactate change over a time period as an indicator of viable tissue, and offers benefits in the management and treatment of the effects of many common diseases, in particular stroke.

Abstract: The present invention provides a novel lactate difference imaging (LDI) technique, allowing assessment of the metabolic responses of tissue over a period of time. This approach utilises lactate change over a time period as an indicator of viable tissue, and offers benefits in the management and treatment of the effects of many common diseases, in particular stroke.

Abstract: An apparatus and a method for obtaining, in vivo, a measurement of retinal response to an optical stimuli. Light sources provide optical stimuli to the retina in accordance with predetermined stimulation sequences, and images of the retina are obtained and correlated with the predetermined stimulation sequences so as to determine responses of the retina to the optical stimuli. In one particular embodiment, optical stimuli are provided according to m-sequences and correlated with corresponding optical coherence tomography images to determine a functional response of the retina.

Abstract: Improved coupling apparatus (10) for coupling an ultrasound probe (24) to an object (26) is described. The apparatus (10) is particularly suitable for use within medical devices. The coupling apparatus (10) comprising first (14) and second (18) deformable coupler located on separate sides of an intermediate layer (16). Employing the first coupler (14) allows the apparatus (10) to be coupled to the probe (24) while the second coupler (18) provides a means for coupling the apparatus (10) to the object (26). The intermediate layer (16) acoustically connects the first (14) and second couplers (18) while providing structural strength for the apparatus (10). Optionally a sheath or cover (157) may be incorporated within the coupling apparatus (141) so as to improve the hygiene and sterile nature of the device.

Abstract: A contrast imaging method e.g. of the T2* weighted “BOLD” type is adapted by use together with an oxygen challenge to provide imaging for the assessment of the metabolic responses of tissue over a period of time the method utilizing three components, oxygen, deoxyhaemoglobin, and oxyhaemoglobin together with time, to provide four variable parameters which allows oxygen to be used as a metabolic marker that can be utilized in an imaging evaluation of soft tissue and organs, e.g. in the study of viable tissue and organ function or dysfunction, which allows utility in diagnosis and assessment of conditions such as cancer, dementia, circulatory disorders, and autoimmune disorders.

Abstract: An apparatus and a method for obtaining, in vivo, a measurement of retinal response to an optical stimuli. Light sources provide optical stimuli to the retina in accordance with predetermined stimulation sequences, and images of the retina are obtained and correlated with the predetermined stimulation sequences so as to determine responses of the retina to the optical stimuli. In one particular embodiment, optical stimuli are provided according to m-sequences and correlated with corresponding optical coherence tomography images to determine a functional response of the retina.

Abstract: Apparatus for the fixation of a fractured bone in a body cavity comprising a plate and a means for holding the plate in position for a period of fixation, wherein the plate is configured such that in use, the plate is positioned supra-mucosally, and wherein the means for holding the plate in position are adapted such that the means can be passed through the mucosa into the fractured bone.

Abstract: Scalp cooling apparatus is describe in which an air flow is recirculated so as to reduce entrained moisture to that initially in the air circuit and to the direct contribution of moisture resulting from evaporation from the scalp, and by matching the impedance between the delivery tubing and evaporation orifice for warm incoming air and chilled outgoing air. In one arrangement an applicator helmet has an air delivery gallery which directs air onto the scalp and hairline through a number of profile drillings of such size and profile as to minimize frictional losses in the air stream. Air is extracted at the crown of the helmet where the convergence and increasing air velocity compensates for increased air temperature so that at this point, scalp cooling is optimized by using the wind-chill effect. The interior of the helmet includes a number of spacers which are held in gentle contact with the scalp by applying a slight force in the helmet using a counter-balanced arm.

Abstract: This invention relates to a dispensing device (1) suitable for use in dispensing a predetermined quantity of material from a container comprising a tubular body member (2) having an outlet (6) at one end, and a plunger (17) slidably movable in said body member. The dispensing device comprises an elongate body (3), and a first drive member (10) mounted in the body (3) for use in driving said plunger (17).According to the invention the first drive member (10) is mounted for driving engagement via an unidirectional drive transmission (12,13), with a second drive member (14) having a free end (15,16) drivingly engagable with the plunger (17) of the container, so that said second drive member (14) and the plunger (17) can be driven by the first drive member (10) via the unidirectional drive transmission members (12,13), only in a direction towards the container outlet (6) while permitting return movement of the first drive member (10).

Abstract: An ultrasonic scanning device having an ultrasonic transmission/reception probe arranged for rapid scanning in a plane while a housing of the device is being held stationary so that real time ultrasonic "pictures" of moving organs such as the heart, can be obtained. The probe is arranged to scan through a window of the housing and mounting means for the probe ensure that ultrasonic signals from the probe have a constant reference point of departure which is at a well-defined small distance from the window. Ultrasonic coupling means are provided between the probe and window, and the window, coupling means and probe may form a sub-assembly removable from the housing.