Abstract: The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an antigen, characterized in that • the antibodies or derivatives or fragments thereof comprise an N-glycan structure free of fucose and xylose, and • at least 90%, preferably at least 95%, more preferred at least 99%, most preferred at least 100% of the modified antibodies, derivatives or fragments thereof lack a C-terminal lysine residue.
Type:
Application
Filed:
July 11, 2007
Publication date:
November 26, 2009
Applicant:
GREENOVATION BIOTECH GMBH
Inventors:
Manfred Schuster, Ralf Kircheis, Andreas Nechansky, Wolfgang Jost, Gilbert Gorr
Abstract: Disclosed are isolated nucleic acid molecules encoding wild type nucleus derived moss expression promoting regions (MEPRs) as well as a method for producing recombinant polypeptides using such MEPRs.
Type:
Grant
Filed:
July 30, 2004
Date of Patent:
May 26, 2009
Assignee:
Greenovation Biotech GmbH
Inventors:
Marta Rodriguez-Franco, Wolfgang Jost, Andreas Weise, Gilbert Gorr
Abstract: A method of amplifying gene expression in a moss plant cell or moss tissue, DNA constructs therefor, moss plant cells and uses thereof for the production of protein.
Abstract: Bryophyte plants and bryophyte plant cells comprising dysfunctional fucT and xylT genes and an introduced glycosyl transferase gene, methods for the production of glycosylated proteins therewith, vectors and uses thereof.
Type:
Application
Filed:
December 18, 2003
Publication date:
June 12, 2008
Applicant:
Greenovation Biotech GmbH
Inventors:
Ralf Reski, Gilbert Gorr, Eva Decker, Christian Stemmer, Otmar Lienhart, Anna Koprivova
Abstract: Disclosed are isolated nucleic acid molecules encoding wild type nucleus derived moss expression promoting regions (MEPRs) as well as a method for producing recombinant polypeptides using such MEPRs.
Type:
Application
Filed:
July 30, 2004
Publication date:
October 19, 2006
Applicant:
Greenovation Biotech GmbH
Inventors:
Marta Rodriguez-Franco, Wolfgang Jost, Andreas Weise, Gilbert Gorr