Patents Assigned to Grenentech, Inc.
  • PYRAZOLE INHIBITORS OF WNT SIGNALING
    Publication number: 20100137394
    Abstract: The invention provides inhibitors of Wnt signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein R1 to R7 and Z are as defined herein.
    Type: Application
    Filed: April 29, 2008
    Publication date: June 3, 2010
    Applicants: Grenentech, Inc., Curis, Inc.
    Inventors: Shirley Ann Brunton, Janet L. Gunzner, Tom Coulter, John H.A Stibbard, James C. Marsters, JR.
  • Thrombolytic agents and thienopyridine derivatives in acute stroke
    Patent number: 5945432
    Abstract: Methods and products are provided for treating thromboembolic stroke. A method involves the administration of a thienopyridine derivative in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke. Preferably the thienopyridine derivative is ticlopidine and the thrombolytic agent is tPA. The method also involves the administration of a thrombolytic agent to a subject who already has circulating plasma levels of a thienopyridine derivative. The product is a pharmaceutical preparation of a thienopyridine derivative and a thrombolytic agent and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: May 1, 1996
    Date of Patent: August 31, 1999
    Assignees: The University of Vermont and State Agricultural College, Grenentech, Inc.
    Inventors: Martin M. Bednar, Bruce A. Keyt, Cordell E. Gross