Patents Assigned to GRI BIO, INC.
  • Prevention and treatment of inflammatory conditions
    Patent number: 11660309
    Abstract: The present embodiments relate to methods for the prevention and treatment of inflammatory conditions such as alcoholic liver disease (ALD). More specifically the present embodiments relate to the prevention and treatment of ALD through the administration of an Retinoic Acid Receptor (RAR) agonist. Some embodiments relate to use of tazarotene in the prevention and treatment of alcohol-induced liver injury, alcohol-related liver disease, fatty liver disease, hepatic steatosis, alcoholic hepatitis or alcoholic cirrhosis.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: May 30, 2023
    Assignee: GRI BIO, INC.
    Inventor: Vipin Kumar Chaturvedi
  • Hydroxy-substituted amino and ammonium derivatives and their medical use
    Patent number: 11564895
    Abstract: The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula 1 or 2, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.
    Type: Grant
    Filed: March 19, 2021
    Date of Patent: January 31, 2023
    Assignee: GRI BIO, INC.
    Inventors: Georg Schlechtingen, Hans-Joachim Knolker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
  • Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
    Patent number: 11453642
    Abstract: The present invention relates to oxygenated amino and ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: September 27, 2022
    Assignee: GRI Bio, Inc.
    Inventors: Georg Schlechtingen, Hans-Joachim Knolker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
  • Hydroxy-substituted amino and ammonium derivatives and their medical use
    Patent number: 10952977
    Abstract: The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula (1) or (2), and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: March 23, 2021
    Assignee: GRI BIO, INC.
    Inventors: Georg Schlechtingen, Hans-Joachim Knolker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
  • Prevention and treatment of inflammatory conditions
    Patent number: 10925886
    Abstract: The present embodiments relate to methods for the prevention and treatment of inflammatory conditions such as alcoholic liver disease (ALD). More specifically the present embodiments relate to the prevention and treatment of ALD through the administration of an Retinoic Acid Receptor (RAR) agonist. Some embodiments relate to use of tazarotene in the prevention and treatment of alcohol-induced liver injury, alcohol-related liver disease, fatty liver disease, hepatic steatosis, alcoholic hepatitis or alcoholic cirrhosis.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: February 23, 2021
    Assignee: GRI BIO, INC.
    Inventor: Vipin Kumar Chaturvedi
  • Amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
    Patent number: 10829506
    Abstract: The present invention relates to amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6 and their medical use, including their use in treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: November 10, 2020
    Assignee: GRI Bio, Inc.
    Inventors: Georg Schlechtingen, Hans-Joachim Knölker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
  • Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
    Patent number: 10815195
    Abstract: The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphoric acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: October 27, 2020
    Assignee: GRI Bio, Inc.
    Inventors: Georg Schlechtingen, Hans-Joachim Knolker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
  • Hydroxy-substituted amino and ammonium derivatives and their medical use
    Patent number: 10143668
    Abstract: The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula (1) or (2), and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: December 4, 2018
    Assignee: GRI BIO, INC.
    Inventors: Georg Schlechtingen, Hans-Joachim Knolker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
  • Prevention and treatment of inflammatory conditions
    Patent number: 9949996
    Abstract: The present embodiments relate to methods for the prevention and treatment of inflammatory conditions such as alcoholic liver disease (ALD). More specifically the present embodiments relate to the prevention and treatment of ALD through the administration of an Retinoic Acid Receptor (RAR) agonist. Some embodiments relate to use of tazarotene in the prevention and treatment of alcohol-induced liver injury, alcohol-related liver disease, fatty liver disease, hepatic steatosis, alcoholic hepatitis or alcoholic cirrhosis.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: April 24, 2018
    Assignee: GRI BIO, INC.
    Inventor: Vipin Kumar Chaturvedi
  • Amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
    Patent number: 9850265
    Abstract: The present invention relates to amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: December 26, 2017
    Assignee: GRI BIO, INC.
    Inventors: Georg Schlechtingen, Hans-Joachim Knölker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
  • Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
    Patent number: 9751834
    Abstract: The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: September 5, 2017
    Assignee: GRI BIO, INC.
    Inventors: Georg Schlechtingen, Hans-Joachim Knölker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier