Patents Assigned to Grieshaber Ophthalmic Research Foundation
  • Patent number: 9561132
    Abstract: The invention relates to a method and a device for treatment of glaucoma, wherein by means of an elongated catheter provided with a distal portion and a proximal portion, a tube-shaped implant is inserted and released in a Schlemm's canal with two opposite openings exposed by an incision and a folded up scleral flap. In a first phase, the distal portion inserted into the Schlemm's canal through the first opening, while a fluid or gaseous medium is injected at the same time, and exited through the second opening, which is, in circumferential direction, oppositely located. The implant detachably disposed at the protruding distal portion and, in a second phase, inserted, in circumferential direction, into the expanded Schlemm's canal up to the first opening. Subsequently, the distal portion, which protrudes from the first opening, is detached from the implant and, together with the catheter, removed.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: February 7, 2017
    Assignee: GRIESHABER OPHTHALMIC RESEARCH FOUNDATION
    Inventors: Robert Christopher Stegmann, Matthias Christian Grieshaber, Hans R. Grieshaber
  • Patent number: 9492319
    Abstract: The invention refers to a tube configured as an implant for insertion at least at one location into the exposed Schlemm's canal of an eye and which, for example, has been mechanically dilated. The elongated tube insertable into the Schlemm's canal includes a plurality openings that are arranged at the tube in axial direction distanced from each other by ring parts and that are in communication with the trabecular tissue the interior space of the tube and the aqueous humor veins of the episcleral vein system and further includes openings oriented in axial direction at a circular arc shaped segment corresponding to the cross section profile of the tube. To realize the natural trabecular aqueous humor drainage, the tube are inserted into the Schlemm's canal that either the openings in the segment are in communication with the aqueous humor veins or that segment with the openings are associated with the trabecular tissue.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: November 15, 2016
    Assignee: GRIESHABER OPHTHALMIC RESEARCH FOUNDATION
    Inventors: Hans R. Grieshaber, Matthias C. Grieshaber, Robert C. Stegmann
  • Patent number: 8951221
    Abstract: The invention relates to a method and device for the treatment of glaucoma, though insertion of an implant into the lumen of the Schlemm's canal to realize proper drainage of the aqueous humor, which implant is brought into its position in the Schlemm's canal by means of a catheter having a distal and a proximate portion and provided with a number of pores through which a gaseous or fluid medium which comes from a pressure source can emerge during insertion of the catheter carrying the implant into the Schlemm's canal, and while the catheter is being inserted into the Schlemm's canal the gaseous or fluid medium is released under pressure thereby expanding the Schlemm's canal and the implant and upon releasing the implant at its determined location, the catheter can be withdrawn from the Schlemm's canal.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: February 10, 2015
    Assignee: Grieshaber Ophthalmic Research Foundation
    Inventors: Robert Christopher Stegmann, Matthias Christian Grieshaber, Hans Rudolf Grieshaber
  • Patent number: 8845572
    Abstract: The invention relates to a method and a device for treatment of glaucoma, wherein by means of an elongated catheter provided with a distal portion and a proximal portion, a tube-shaped implant is inserted and released in a Schlemm's canal with two opposite openings exposed by an incision and a folded up scleral flap. In a first phase, the distal portion inserted into the Schlemm's canal through the first opening, while a fluid or gaseous medium is injected at the same time, and exited through the second opening, which is, in circumferential direction, oppositely located. The implant detachably disposed at the protruding distal portion and, in a second phase, inserted, in circumferential direction, into the expanded Schlemm's canal up to the first opening. Subsequently, the distal portion, which protrudes from the first opening, is detached from the implant and, together with the catheter, removed.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: September 30, 2014
    Assignee: Grieshaber Ophthalmic Research Foundation
    Inventors: Robert Christopher Stegmann, Matthias Christian Grieshaber, Hans R. Grieshaber
  • Publication number: 20130331760
    Abstract: The invention refers to a tube configured as an implant for insertion at least at one location into the exposed Schlemm's canal of an eye and which, for example, has been mechanically dilated. The elongated tube insertable into the Schlemm's canal includes a plurality openings that are arranged at the tube in axial direction distanced from each other by ring parts and that are in communication with the trabecular tissue the interior space of the tube and the aqueous humor veins of the episcleral vein system and further includes openings oriented in axial direction at a circular arc shaped segment corresponding to the cross section profile of the tube. To realize the natural trabecular aqueous humor drainage, the tube are inserted into the Schlemm's canal that either the openings in the segment are in communication with the aqueous humor veins or that segment with the openings are associated with the trabecular tissue.
    Type: Application
    Filed: August 13, 2013
    Publication date: December 12, 2013
    Applicant: Grieshaber Ophthalmic Research Foundation
    Inventors: Hans R. Grieshaber, Matthias C. Grieshaber, Robert C. Stegmann
  • Publication number: 20120310072
    Abstract: A method and device are proposed for carrying out ophthalmologic analyses especially for the pathological evaluation of the Schlemm's canal that has been exposed through a scleral flap and into which an micro catheter is inserted that also includes a medium line by means of which medium is brought into the lumen of the Schlemm's canal for dilating the lumen and a light guide for illumination such that analog images of the dilated lumen, the inner wall of the trabecular tissue and the veins of the aqueous humor can be taken by a camera and transmitted to an outside monitor for visual evaluation.
    Type: Application
    Filed: June 2, 2011
    Publication date: December 6, 2012
    Applicant: GRIESHABER OPHTHALMIC RESEARCH FOUNDATION
    Inventor: HANS R. GRIESHABER
  • Publication number: 20110118649
    Abstract: The invention relates to a method and a device for treatment of glaucoma, wherein by means of an elongated catheter provided with a distal portion and a proximal portion, a tube-shaped implant is inserted and released in a Schlemm's canal with two opposite openings exposed by an incision and a folded up scleral flap. In a first phase, the distal portion inserted into the Schlemm's canal through the first opening, while a fluid or gaseous medium is injected at the same time, and exited through the second opening, which is, in circumferential direction, oppositely located. The implant detachably disposed at the protruding distal portion and, in a second phase, inserted, in circumferential direction, into the expanded Schlemm's canal up to the first opening. Subsequently, the distal portion, which protrudes from the first opening, is detached from the implant and, together with the catheter, removed.
    Type: Application
    Filed: November 13, 2009
    Publication date: May 19, 2011
    Applicant: Grieshaber Ophthalmic Research Foundation
    Inventors: Robert Stegmann, Matthias Grieshaber, Hans Grieshaber
  • Publication number: 20110046536
    Abstract: The invention relates to a method and device for the treatment of glaucoma, though insertion of an implant into the lumen of the Schlemm's canal to realize proper drainage of the aqueous humor, which implant is brought into its position in the Schlemm's canal by means of a catheter having a distal and a proximate portion and provided with a number of pores through which a gaseous or fluid medium which comes from a pressure source can emerge during insertion of the catheter carrying the implant into the Schlemm's canal, and while the catheter is being inserted into the Schlemm's canal the gaseous or fluid medium is released under pressure thereby expanding the Schlemm's canal and the implant and upon releasing the implant at its determined location, the catheter can be withdrawn from the Schlemm's canal.
    Type: Application
    Filed: August 20, 2009
    Publication date: February 24, 2011
    Applicant: Grieshaber Ophthalmic Research Foundation
    Inventors: Robert Christopher Stegmann, Matthias Christian Grieshaber, Hans Rudolf Grieshaber